Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DT351_RS06250 Genome accession   NZ_CP031003
Coordinates   1206705..1207376 (-) Length   223 a.a.
NCBI ID   WP_004270751.1    Uniprot ID   A0A1B2A7J9
Organism   Latilactobacillus curvatus strain TMW 1.1928     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1201705..1212376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DT351_RS06225 (DT351_06225) rpsO 1202018..1202287 (-) 270 WP_004271112.1 30S ribosomal protein S15 -
  DT351_RS06230 (DT351_06230) rpsT 1202564..1202818 (+) 255 WP_004271117.1 30S ribosomal protein S20 -
  DT351_RS06235 (DT351_06235) holA 1202874..1203902 (-) 1029 WP_089542075.1 DNA polymerase III subunit delta -
  DT351_RS06240 (DT351_06240) comEC 1203903..1206017 (-) 2115 WP_223315707.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DT351_RS06245 (DT351_06245) - 1206158..1206646 (-) 489 WP_004270740.1 ComE operon protein 2 -
  DT351_RS06250 (DT351_06250) comEA 1206705..1207376 (-) 672 WP_004270751.1 helix-hairpin-helix domain-containing protein Machinery gene
  DT351_RS06255 (DT351_06255) - 1207453..1208499 (-) 1047 WP_080563410.1 SepM family pheromone-processing serine protease -
  DT351_RS06260 (DT351_06260) coaD 1208501..1208995 (-) 495 WP_065825725.1 pantetheine-phosphate adenylyltransferase -
  DT351_RS06265 (DT351_06265) rsmD 1209007..1209561 (-) 555 WP_004270750.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DT351_RS06270 (DT351_06270) - 1209567..1209857 (-) 291 WP_004270748.1 YlbG family protein -
  DT351_RS06275 (DT351_06275) - 1209877..1210965 (-) 1089 WP_065825727.1 CAP-associated domain-containing protein -
  DT351_RS06280 (DT351_06280) - 1210978..1212165 (-) 1188 WP_004270744.1 putative peptidoglycan glycosyltransferase FtsW -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24849.51 Da        Isoelectric Point: 9.9048

>NTDB_id=302778 DT351_RS06250 WP_004270751.1 1206705..1207376(-) (comEA) [Latilactobacillus curvatus strain TMW 1.1928]
MWRDYWQRYRRFWWVPCLVIILLGGGVFWQHSRQQRFLSTNQQLMAQSTKRKVKAKPVKQKKSVSKGGFVDIKGAVAHPG
IYPICVAKTRLFEVLKQAGDVTEAADTSQLNLAQTLSDQLIIYVPTKGEAVQAEELVKAADEPQAATDNQAGASPISTDA
KINLNQADATQLQTLNGIGPKKAEQIIAYRDEQGQFKQIEDLQKVGGIGPKTFEQLRPQICVN

Nucleotide


Download         Length: 672 bp        

>NTDB_id=302778 DT351_RS06250 WP_004270751.1 1206705..1207376(-) (comEA) [Latilactobacillus curvatus strain TMW 1.1928]
ATGTGGCGCGACTATTGGCAACGGTATCGTCGATTCTGGTGGGTACCTTGTTTGGTGATAATTTTACTTGGTGGTGGTGT
GTTTTGGCAGCATAGTCGGCAACAACGTTTTCTATCAACCAATCAACAATTGATGGCGCAATCAACTAAGCGAAAAGTGA
AGGCAAAACCCGTCAAACAGAAGAAAAGCGTCTCAAAAGGTGGGTTTGTCGATATCAAAGGCGCTGTGGCACATCCAGGG
ATTTATCCGATTTGTGTTGCAAAGACGCGTTTATTTGAGGTGCTGAAACAAGCGGGGGATGTGACCGAAGCAGCGGATAC
GAGTCAGTTGAACTTAGCGCAAACATTGAGTGACCAACTTATTATCTATGTGCCAACTAAGGGAGAAGCGGTGCAAGCCG
AAGAATTAGTGAAAGCGGCAGACGAGCCACAGGCTGCGACTGACAATCAAGCGGGAGCCAGTCCGATATCAACTGATGCT
AAAATCAACCTAAACCAAGCGGATGCGACACAATTGCAAACGCTAAATGGCATCGGTCCTAAAAAAGCTGAACAAATAAT
TGCATATCGGGATGAGCAAGGGCAGTTTAAACAAATCGAAGATCTTCAAAAAGTTGGGGGAATTGGGCCGAAAACGTTTG
AACAATTACGGCCACAAATTTGTGTTAATTAG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(70-115)

Helix-hairpin-helix motif (HHH_3)

(160-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B2A7J9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Latilactobacillus sakei subsp. sakei 23K

64.53

100

0.677
  comEA Lactococcus lactis subsp. cremoris KW2

36.283

100

0.368

Multiple sequence alignment