Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ETT53_RS08415 Genome accession   NZ_CP035446
Coordinates   1679642..1680238 (-) Length   198 a.a.
NCBI ID   WP_011185063.1    Uniprot ID   A2RGV1
Organism   Streptococcus pyogenes strain emm68.2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1674642..1685238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT53_RS08380 (ETT53_08375) - 1674702..1675007 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ETT53_RS08385 (ETT53_08380) ruvX 1675019..1675438 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ETT53_RS08390 (ETT53_08385) - 1675435..1675704 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ETT53_RS08395 (ETT53_08390) spx 1675818..1676216 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ETT53_RS08400 (ETT53_08395) recA 1676507..1677643 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  ETT53_RS08405 (ETT53_08400) cinA 1677732..1679003 (-) 1272 WP_032459984.1 competence/damage-inducible protein A Machinery gene
  ETT53_RS08410 (ETT53_08405) - 1679072..1679632 (-) 561 WP_111703697.1 DNA-3-methyladenine glycosylase I -
  ETT53_RS08415 (ETT53_08410) ruvA 1679642..1680238 (-) 597 WP_011185063.1 Holliday junction branch migration protein RuvA Machinery gene
  ETT53_RS08420 (ETT53_08415) - 1680240..1681460 (-) 1221 WP_011529098.1 MFS transporter -
  ETT53_RS08425 (ETT53_08420) hexB 1681471..1683453 (-) 1983 WP_129321532.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21852.19 Da        Isoelectric Point: 6.4948

>NTDB_id=302735 ETT53_RS08415 WP_011185063.1 1679642..1680238(-) (ruvA) [Streptococcus pyogenes strain emm68.2]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=302735 ETT53_RS08415 WP_011185063.1 1679642..1680238(-) (ruvA) [Streptococcus pyogenes strain emm68.2]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGGTTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAACAGAGCTGAAAAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RGV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae R6

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae D39

66.497

99.495

0.662
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.394

100

0.414

Multiple sequence alignment