Detailed information NTG0302635

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: DS740_RS19190
• Genome accession: NZ_CP030937
• Coordinates: 3660242..3661399 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus sp. DM2
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3655242..3666399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DS740_RS19160 (DS740_19160)	-	3655495..3655914 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
DS740_RS19165 (DS740_19165)	comFC	3655988..3656710 (-)	723	WP_014481051.1	comF operon protein ComFC	Machinery gene
DS740_RS19170 (DS740_19170)	comFB	3656674..3656970 (-)	297	WP_003227989.1	late competence protein ComFB	-
DS740_RS19175 (DS740_19175)	comFA	3657030..3658421 (-)	1392	WP_041850475.1	ATP-dependent helicase ComFA	Machinery gene
DS740_RS19180 (DS740_19180)	-	3658527..3659372 (-)	846	WP_003227986.1	DegV family protein	-
DS740_RS19185 (DS740_19185)	degU	3659470..3660159 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
DS740_RS19190 (DS740_19190)	degS	3660242..3661399 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
DS740_RS19195 (DS740_19195)	-	3661616..3662269 (+)	654	WP_003227979.1	YigZ family protein	-
DS740_RS19200 (DS740_19200)	tagV	3662269..3663453 (+)	1185	WP_041850474.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
DS740_RS19205 (DS740_19205)	-	3663526..3664602 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
DS740_RS19210 (DS740_19210)	-	3664747..3665940 (-)	1194	WP_080332566.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=302635 DS740_RS19190 WP_003227983.1 3660242..3661399(-) (degS) [Bacillus sp. DM2]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=302635 DS740_RS19190 WP_003227983.1 3660242..3661399(-) (degS) [Bacillus sp. DM2]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGTGAGCAGTCACGCCAGCAGTATGAACAGCTGGTTGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCAGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1