Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT56_RS03620 Genome accession   NZ_CP035443
Coordinates   691047..691709 (+) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain emm58     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 686047..696709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT56_RS03600 (ETT56_03600) - 686911..688911 (+) 2001 WP_023610608.1 potassium transporter Kup -
  ETT56_RS03605 (ETT56_03605) - 688935..689213 (-) 279 WP_011017953.1 GIY-YIG nuclease family protein -
  ETT56_RS03610 (ETT56_03610) - 689203..689979 (-) 777 WP_010922438.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT56_RS03615 (ETT56_03615) - 690097..690837 (+) 741 WP_012560804.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT56_RS03620 (ETT56_03620) comEA/celA/cilE 691047..691709 (+) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  ETT56_RS03625 (ETT56_03625) comEC/celB 691690..693933 (+) 2244 WP_063632926.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT56_RS03630 (ETT56_03630) holA 694004..695044 (+) 1041 WP_011888795.1 DNA polymerase III subunit delta -
  ETT56_RS03635 (ETT56_03635) sodA 695141..695746 (+) 606 WP_023610389.1 superoxide dismutase SodA -
  ETT56_RS03640 (ETT56_03640) - 695913..696146 (+) 234 WP_002983979.1 hypothetical protein -
  ETT56_RS09840 (ETT56_03645) - 696147..696374 (+) 228 WP_226316535.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=302415 ETT56_RS03620 WP_002995626.1 691047..691709(+) (comEA/celA/cilE) [Streptococcus pyogenes strain emm58]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=302415 ETT56_RS03620 WP_002995626.1 691047..691709(+) (comEA/celA/cilE) [Streptococcus pyogenes strain emm58]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405

Multiple sequence alignment