Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT59_RS03470 Genome accession   NZ_CP035440
Coordinates   668143..668805 (+) Length   220 a.a.
NCBI ID   WP_136305985.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm124     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 663143..673805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT59_RS03450 (ETT59_03450) - 664017..666017 (+) 2001 WP_136305986.1 potassium transporter Kup -
  ETT59_RS03455 (ETT59_03455) - 666041..666319 (-) 279 WP_011017953.1 GIY-YIG nuclease family protein -
  ETT59_RS03460 (ETT59_03460) - 666309..667085 (-) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT59_RS03465 (ETT59_03465) - 667203..667943 (+) 741 WP_012560804.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT59_RS03470 (ETT59_03470) comEA/celA/cilE 668143..668805 (+) 663 WP_136305985.1 ComEA family DNA-binding protein Machinery gene
  ETT59_RS03475 (ETT59_03475) comEC/celB 668786..671029 (+) 2244 WP_136276413.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT59_RS03480 (ETT59_03480) holA 671100..672140 (+) 1041 WP_011888795.1 DNA polymerase III subunit delta -
  ETT59_RS03485 (ETT59_03485) sodA 672237..672842 (+) 606 WP_023612500.1 superoxide dismutase SodA -
  ETT59_RS03490 (ETT59_03490) - 673009..673236 (+) 228 WP_136276409.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24624.39 Da        Isoelectric Point: 5.8311

>NTDB_id=302128 ETT59_RS03470 WP_136305985.1 668143..668805(+) (comEA/celA/cilE) [Streptococcus pyogenes strain emm124]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEETLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=302128 ETT59_RS03470 WP_136305985.1 668143..668805(+) (comEA/celA/cilE) [Streptococcus pyogenes strain emm124]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAGAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.512

94.091

0.4

Multiple sequence alignment