Detailed information    

insolico Bioinformatically predicted

Overview

Name   ctsE   Type   Machinery gene
Locus tag   DSQ35_RS07490 Genome accession   NZ_CP030866
Coordinates   1446662..1448221 (-) Length   519 a.a.
NCBI ID   WP_002864463.1    Uniprot ID   Q0P8E6
Organism   Campylobacter jejuni strain CS17     
Function   type II secretion system/type IV pilin; DNA uptake (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1430554..1448146 1446662..1448221 flank -1484


Gene organization within MGE regions


Location: 1430554..1448221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DSQ35_RS07370 (DSQ35_1461) - 1431900..1433138 (+) 1239 WP_052803393.1 phage minor head protein -
  DSQ35_RS07375 (DSQ35_1462) - 1433264..1433638 (+) 375 WP_002876309.1 phage tail protein -
  DSQ35_RS07380 (DSQ35_1463) - 1433631..1433822 (+) 192 WP_002784520.1 tail protein X -
  DSQ35_RS07385 (DSQ35_1464) - 1433816..1434793 (+) 978 WP_116480900.1 phage late control D family protein -
  DSQ35_RS07390 (DSQ35_1465) - 1434790..1435074 (-) 285 WP_002784523.1 Mor transcription activator family protein -
  DSQ35_RS07395 (DSQ35_1466) - 1435168..1435839 (+) 672 WP_002876312.1 endonuclease -
  DSQ35_RS07400 (DSQ35_1467) - 1435831..1436106 (-) 276 WP_002873721.1 hypothetical protein -
  DSQ35_RS07405 (DSQ35_1468) - 1436153..1436602 (-) 450 WP_260383882.1 regulatory protein GemA -
  DSQ35_RS07410 (DSQ35_1469) - 1436599..1437291 (-) 693 WP_052774290.1 hypothetical protein -
  DSQ35_RS07415 (DSQ35_1470) - 1437291..1437560 (-) 270 WP_002784531.1 hypothetical protein -
  DSQ35_RS07420 (DSQ35_1471) - 1437557..1438519 (-) 963 WP_253697187.1 AAA family ATPase -
  DSQ35_RS07425 (DSQ35_1472) - 1438628..1439053 (-) 426 WP_052774289.1 YopX family protein -
  DSQ35_RS07430 (DSQ35_1473) - 1439050..1439322 (-) 273 WP_002791414.1 hypothetical protein -
  DSQ35_RS07435 (DSQ35_1475) - 1439386..1439571 (-) 186 WP_002824160.1 hypothetical protein -
  DSQ35_RS07440 (DSQ35_1476) - 1439568..1440053 (-) 486 WP_253697183.1 host-nuclease inhibitor Gam family protein -
  DSQ35_RS07445 (DSQ35_1477) - 1440160..1440501 (-) 342 WP_002824158.1 DUF4406 domain-containing protein -
  DSQ35_RS07450 (DSQ35_1478) - 1440558..1440743 (-) 186 WP_002824157.1 hypothetical protein -
  DSQ35_RS07455 (DSQ35_1479) - 1440740..1440931 (-) 192 WP_052774287.1 sigma factor-like helix-turn-helix DNA-binding protein -
  DSQ35_RS07460 (DSQ35_1480) - 1440934..1441857 (-) 924 WP_002806833.1 AAA family ATPase -
  DSQ35_RS07465 (DSQ35_1481) - 1441928..1444003 (-) 2076 WP_032593272.1 DDE-type integrase/transposase/recombinase -
  DSQ35_RS07470 (DSQ35_1482) - 1444000..1444200 (-) 201 WP_002826948.1 hypothetical protein -
  DSQ35_RS07475 (DSQ35_1484) - 1444350..1445024 (+) 675 WP_253697180.1 S24 family peptidase -
  DSQ35_RS07480 (DSQ35_1485) - 1445024..1445725 (+) 702 WP_002826961.1 hypothetical protein -
  DSQ35_RS07485 (DSQ35_1486) - 1445802..1446665 (-) 864 Protein_1460 type II secretion system F family protein -
  DSQ35_RS07490 (DSQ35_1487) ctsE 1446662..1448221 (-) 1560 WP_002864463.1 GspE/PulE family protein Machinery gene

Sequence

Protein


Download         Length: 519 a.a.        Molecular weight: 60117.90 Da        Isoelectric Point: 5.8188

>NTDB_id=301968 DSQ35_RS07490 WP_002864463.1 1446662..1448221(-) (ctsE) [Campylobacter jejuni strain CS17]
MESRMDKIFQAYIDNEISLDEICTKFNITSWDFFNKLANFCNLHFVDLDEDNDFIYEGIPFSLLLKFKFLLIKNNDGFMI
IRSKPCSLELLEQVKTFMICEKIDTAIADELKIAKILNQIRIQEEIKRLSIKLRLEWQENHKRDDQSCISQIFDFLLHEI
LSFHASDIHIEARNNDALIRFRVDGILREFAIFEKDIYEALVFHVKFLACLNLAESRKTQDGSFELDFENERYDFRVSCL
PLIYGESVVIRILKHDKEILDLYKLNLGNKNLEILKKILHRPNGMILLTGPTGSGKSTTLYACLNELKSIEKKIISAEDP
IEYKIPLVQQILLNSKVGVEFNSVLRAILRQDPDIIMIGEIRDEESLDIALKASLTGHLLLSTLHTNDALSTIDRLLDMQ
AKSYLIASALSLVIAQRLVRKLCPWCKQKSKKHYIEFEGEFFEPKGCERCHHSGFFGRELIAECLEINEDLACAIRENQD
KTILMELAKKYGFQTMFEQGLKKAKEGLTSIDELLRVVR

Nucleotide


Download         Length: 1560 bp        

>NTDB_id=301968 DSQ35_RS07490 WP_002864463.1 1446662..1448221(-) (ctsE) [Campylobacter jejuni strain CS17]
ATGGAAAGTAGAATGGATAAAATTTTTCAAGCTTATATTGATAATGAAATAAGTCTTGATGAAATTTGCACTAAATTTAA
TATCACTTCTTGGGATTTTTTTAACAAATTAGCAAATTTTTGTAATTTACATTTTGTTGATTTAGATGAAGATAATGATT
TTATTTATGAAGGTATACCTTTTTCTTTACTTTTAAAATTTAAATTTCTGCTTATTAAAAACAATGACGGCTTTATGATT
ATTAGATCCAAACCTTGTTCTTTAGAGCTTTTAGAGCAAGTTAAGACTTTTATGATTTGTGAAAAAATCGACACTGCAAT
TGCCGATGAATTAAAGATAGCTAAAATTTTAAATCAAATTCGCATTCAAGAGGAGATTAAAAGATTAAGCATTAAGCTTA
GACTTGAATGGCAAGAAAATCACAAAAGAGATGATCAAAGTTGCATCAGTCAAATTTTTGATTTTTTATTACATGAAATT
TTATCTTTTCATGCGAGTGATATTCATATAGAGGCAAGAAATAATGATGCTTTGATTAGGTTTAGGGTTGATGGAATTTT
GCGTGAATTTGCTATTTTTGAGAAGGATATTTATGAAGCTTTGGTTTTTCATGTCAAATTTTTAGCTTGTTTGAATTTAG
CTGAATCAAGAAAAACACAAGATGGAAGTTTTGAATTAGATTTTGAAAATGAAAGATATGATTTTCGTGTTTCATGTTTG
CCTTTGATTTATGGCGAAAGTGTTGTTATAAGAATTTTAAAACATGATAAAGAAATTTTGGATTTGTATAAACTAAATCT
TGGAAATAAAAATTTAGAAATTTTAAAAAAGATTTTACATCGTCCCAATGGAATGATTTTATTAACCGGTCCTACAGGTA
GTGGTAAAAGCACAACTTTATACGCGTGTTTAAATGAGTTGAAAAGTATTGAAAAAAAGATTATTTCCGCAGAAGATCCT
ATAGAATATAAAATTCCTTTAGTGCAGCAAATTTTGCTCAATTCAAAAGTTGGAGTCGAGTTTAATAGTGTTTTAAGAGC
AATTTTAAGGCAAGATCCTGATATTATCATGATAGGAGAAATTCGCGATGAAGAAAGTTTAGATATTGCACTTAAAGCTT
CTTTAACAGGTCATTTGCTTTTAAGCACCTTGCATACTAATGATGCTCTTAGTACCATTGATAGGCTTTTGGATATGCAA
GCAAAAAGTTACTTGATAGCATCGGCTTTGAGTCTTGTTATAGCACAGCGTTTGGTTAGAAAACTTTGTCCTTGGTGTAA
GCAAAAAAGCAAAAAACATTATATTGAATTTGAAGGTGAATTTTTTGAACCAAAAGGATGTGAGCGTTGTCATCATAGTG
GATTTTTTGGCAGAGAATTAATCGCTGAGTGCTTAGAGATCAATGAAGATTTAGCTTGTGCAATTAGGGAAAATCAAGAT
AAAACGATTTTAATGGAGCTTGCAAAAAAATATGGCTTTCAAACTATGTTTGAACAAGGTTTAAAAAAAGCCAAAGAAGG
TCTTACAAGTATAGATGAGCTTTTAAGGGTTGTAAGATGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(157-421)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P8E6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ctsE Campylobacter jejuni subsp. jejuni 81-176

99.615

100

0.996

Multiple sequence alignment