Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   ETT63_RS08750 Genome accession   NZ_CP035436
Coordinates   1728391..1729158 (-) Length   255 a.a.
NCBI ID   WP_115219873.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm89.14     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1723391..1734158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT63_RS08735 (ETT63_08730) hexB 1723849..1725831 (-) 1983 WP_136267866.1 DNA mismatch repair endonuclease MutL Machinery gene
  ETT63_RS08740 (ETT63_08735) - 1725926..1727077 (-) 1152 WP_023612650.1 site-specific integrase -
  ETT63_RS08745 (ETT63_08740) - 1727399..1727542 (+) 144 WP_011185066.1 putative holin-like toxin -
  ETT63_RS08750 (ETT63_08745) irvR 1728391..1729158 (-) 768 WP_115219873.1 helix-turn-helix transcriptional regulator Regulator
  ETT63_RS08755 (ETT63_08750) - 1729312..1729518 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  ETT63_RS08765 (ETT63_08760) - 1729552..1730224 (+) 673 Protein_1621 BRO family protein -
  ETT63_RS08770 (ETT63_08765) - 1730234..1730839 (+) 606 WP_136267867.1 Bro-N domain-containing protein -
  ETT63_RS08775 (ETT63_08770) - 1730860..1731267 (+) 408 WP_002992501.1 hypothetical protein -
  ETT63_RS09425 - 1731280..1731402 (+) 123 WP_011285272.1 hypothetical protein -
  ETT63_RS08780 (ETT63_08775) - 1731685..1732206 (+) 522 WP_227875683.1 Rha family transcriptional regulator -
  ETT63_RS08790 (ETT63_08785) - 1732845..1733018 (+) 174 WP_000074663.1 plasmid mobilization protein -
  ETT63_RS08795 (ETT63_08790) - 1733204..1733608 (+) 405 WP_227868741.1 hypothetical protein -
  ETT63_RS08800 (ETT63_08795) - 1733710..1734042 (+) 333 WP_011285276.1 hypothetical protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28752.03 Da        Isoelectric Point: 4.3544

>NTDB_id=301791 ETT63_RS08750 WP_115219873.1 1728391..1729158(-) (irvR) [Streptococcus pyogenes strain emm89.14]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNNNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=301791 ETT63_RS08750 WP_115219873.1 1728391..1729158(-) (irvR) [Streptococcus pyogenes strain emm89.14]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAATAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33

100

0.388

Multiple sequence alignment