Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   ETT63_RS05580 Genome accession   NZ_CP035436
Coordinates   1081397..1083493 (+) Length   698 a.a.
NCBI ID   WP_136267092.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm89.14     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1076397..1088493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT63_RS05555 (ETT63_05555) deoD 1076420..1077133 (-) 714 WP_136075104.1 purine-nucleoside phosphorylase -
  ETT63_RS05560 (ETT63_05560) - 1077799..1078608 (-) 810 WP_136075103.1 purine-nucleoside phosphorylase -
  ETT63_RS05565 (ETT63_05565) arsC 1078592..1079032 (-) 441 WP_136267263.1 arsenate reductase (glutaredoxin) -
  ETT63_RS05570 (ETT63_05570) - 1079048..1080259 (-) 1212 WP_136046443.1 phosphopentomutase -
  ETT63_RS05575 (ETT63_05575) rpiA 1080336..1081019 (-) 684 WP_136116769.1 ribose-5-phosphate isomerase RpiA -
  ETT63_RS05580 (ETT63_05580) clpC 1081397..1083493 (+) 2097 WP_136267092.1 AAA family ATPase Regulator
  ETT63_RS05585 (ETT63_05585) - 1083551..1084294 (-) 744 WP_002984942.1 hypothetical protein -
  ETT63_RS05590 (ETT63_05590) yihA 1084442..1085041 (-) 600 WP_011184414.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ETT63_RS05595 (ETT63_05595) clpX 1085051..1086280 (-) 1230 WP_009880296.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ETT63_RS05600 (ETT63_05600) - 1086410..1086580 (-) 171 WP_002990165.1 hypothetical protein -
  ETT63_RS05605 (ETT63_05605) - 1086600..1087097 (-) 498 WP_136047827.1 dihydrofolate reductase -
  ETT63_RS05610 (ETT63_05610) - 1087177..1088016 (-) 840 WP_002990167.1 thymidylate synthase -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 77207.32 Da        Isoelectric Point: 5.7799

>NTDB_id=301765 ETT63_RS05580 WP_136267092.1 1081397..1083493(+) (clpC) [Streptococcus pyogenes strain emm89.14]
MTHFSGKDPFVNMDDIFNQLMADMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFYDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTV
IIATSNAGFGQQDTETSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDAK
AHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQKDQ

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=301765 ETT63_RS05580 WP_136267092.1 1081397..1083493(+) (clpC) [Streptococcus pyogenes strain emm89.14]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAGACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTCGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCCGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTTATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAATCA
TTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACCGTT
ATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGGGTCTAACATTATGGATCGCATTGCACC
TTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAGAAA
TTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCTAAA
GCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCGTGA
CCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATTCTAAAAGAAGGACAACTAGTGATTA
GGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(259-353)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(606-677)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-599)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.436

100

0.477
  clpE Streptococcus mutans UA159

46.733

100

0.471
  clpE Streptococcus pneumoniae Rx1

49.518

89.112

0.441
  clpE Streptococcus pneumoniae R6

49.518

89.112

0.441
  clpE Streptococcus pneumoniae D39

49.518

89.112

0.441
  clpE Streptococcus pneumoniae TIGR4

49.518

89.112

0.441
  clpC Bacillus subtilis subsp. subtilis str. 168

44.729

95.129

0.426
  clpC Streptococcus pneumoniae TIGR4

41.493

95.989

0.398
  clpC Streptococcus thermophilus LMD-9

42.857

91.261

0.391
  clpC Streptococcus pneumoniae D39

41.935

93.266

0.391
  clpC Streptococcus pneumoniae Rx1

41.935

93.266

0.391
  clpC Streptococcus thermophilus LMG 18311

42.654

90.688

0.387
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.411

93.41

0.387
  clpC Streptococcus mutans UA159

41.628

91.547

0.381

Multiple sequence alignment