Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DRA65_RS00275 Genome accession   NZ_CP030826
Coordinates   56093..59206 (-) Length   1037 a.a.
NCBI ID   WP_101135504.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 11-251     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 51093..64206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DRA65_RS00255 - 51681..51848 (-) 168 WP_153312129.1 hypothetical protein -
  DRA65_RS00260 (DRA65_00305) - 51852..52241 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  DRA65_RS00265 (DRA65_00320) - 52820..52957 (-) 138 WP_002214606.1 VOC family protein -
  DRA65_RS00270 (DRA65_00325) carA 53003..54136 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DRA65_RS00275 (DRA65_00355) pilC 56093..59206 (-) 3114 WP_101135504.1 PilC family type IV pilus tip adhesin Machinery gene
  DRA65_RS00280 (DRA65_00370) apbC 60160..61238 (-) 1079 Protein_53 iron-sulfur cluster carrier protein ApbC -
  DRA65_RS00290 (DRA65_00380) - 61603..62112 (+) 510 WP_002224078.1 protein disulfide oxidoreductase -
  DRA65_RS00295 (DRA65_00390) nadR 62455..62895 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DRA65_RS00300 (DRA65_00395) hpaC 63010..63510 (+) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1037 a.a.        Molecular weight: 113385.26 Da        Isoelectric Point: 9.7038

>NTDB_id=301748 DRA65_RS00275 WP_101135504.1 56093..59206(-) (pilC) [Neisseria meningitidis strain 11-251]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAQAETHNYAIVMNEQNQLKVKQKDSYSTLREKDRERKFIYNKGWQGGGSVL
FDNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDANALKERNNAVDWIHTTRAGLAGYAYTNVICRSHQCPQLVYKTRFSF
DNPDLAKRGGGLDRHTEPSRDNSLIYKLKDHPWLGVSFNLGSENTVKNSQSSSRLISSFSEDNNNQTIVSTTENHPISLG
DGQREHTAVAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQRTGLGGLLGFHAKWDIKDTGQIPVELGLPQIKA
GRCINKPNPNPKAQALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSEI
KSKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGVDPDASEWKKVLLPWTVRASNDDNQFKTINQ
QLNQQKIQYSQRYRIRDNGNRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDNDT
SALKDSTLAKELRTFAEKGYVGDRYGVDGGFVLRKVERNGKDHVFMFGAMGFGGRGAYALDLTKADGSDPTAVSLFDVKN
DNNGKNSNNSNNSVELGYTVGTPQIGKTHNGKYAAFLASGYATKDINNGDNKTALYVYDLESSGTLIKKIEVPNSKGGLS
SPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSGQDPNQWSVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDVLS
TDEQHIYGIFDDDTATTGSVNFSGLGGGLLEQELKQEGKTLFLTDYKRSDGSGNKGWVVKLKEGQRVTVKPTVVLRTAFV
TIHKYTGTDKCGAETAILGINTADGGKLTKKSARPIVPEANTAVAQYSGHKQTANGKSIPIGCMQKGNEIVCPNGYVYDK
PVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3114 bp        

>NTDB_id=301748 DRA65_RS00275 WP_101135504.1 56093..59206(-) (pilC) [Neisseria meningitidis strain 11-251]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGGGG
GGGGGGGGCGCAGGCGGAAACCCATAACTACGCTATTGTCATGAACGAACAAAATCAGCTGAAGGTAAAGCAGAAGGATT
CATATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGGCTGGCAGGGTGGAGGCTCTGTCTTG
TTCGACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCAACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCGGGCCGGGC
TGGCAGGCTACGCCTACACCAACGTCATATGCAGAAGCCACCAATGCCCCCAACTTGTCTATAAAACCCGATTTTCCTTC
GATAATCCCGACTTGGCAAAAAGAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCTCATTTACAA
ATTGAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCCAATCATCCAGCA
GATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAAACCACCCTATTTCCCTTGGC
GACGGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAAAGA
TATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAGGACGGGGCTTGGCGGCT
TGCTAGGTTTTCATGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCGGTCGAGCTCGGCCTGCCGCAAATCAAAGCA
GGCCGCTGCATCAACAAACCGAACCCCAATCCCAAAGCCCAAGCCCTTTCGCCGGCACTGACTGCCCCCGCGCTGTGGTT
CGGACCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAATTT
TCCTGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAGATT
AAAAGTAAAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACAGCAGATTAAACTTCAAGG
CAATGAGGTCACTAGTTTTAATGTAAACAACGGCAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATG
CCAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACAATCAATTTAAAACAATTAACCAA
CAACTTAACCAACAAAAAATCCAATACAGCCAAAGATACCGCATCCGCGACAACGGCAATCGCGATTTGGGCGACATCGT
CAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCG
GCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACT
TCCGCTCTCAAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGT
GGACGGCGGCTTTGTCTTGCGCAAAGTCGAACGGAACGGGAAAGACCATGTGTTTATGTTCGGCGCGATGGGCTTTGGCG
GCAGAGGTGCATACGCCTTGGATTTGACCAAAGCCGACGGCAGTGACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAAT
GACAATAATGGCAAGAATAGCAATAATAGCAATAATAGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAA
AACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGACATTAACAACGGCGACAATAAAACCG
CGCTGTATGTATATGATTTGGAAAGCAGCGGCACGCTGATTAAAAAAATCGAAGTACCCAACAGCAAGGGCGGGCTTTCG
TCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCG
CTTTGATTTGAGCGGTCAAGATCCTAATCAATGGTCTGTACGCACCATTTTCAGCGGCAACAAACCGATTACTTCCGCGC
CCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGTACGGGCAGTGATTTGAGTGAGGAGGATGTACTCAGT
ACGGATGAACAACATATTTACGGTATCTTCGACGACGATACGGCGACGACGGGTAGTGTAAACTTCAGCGGTTTGGGAGG
CGGGCTGCTCGAGCAAGAGCTTAAGCAGGAGGGTAAAACCTTATTCCTGACCGATTATAAGCGATCCGACGGCTCGGGCA
ATAAGGGGTGGGTAGTGAAGCTGAAGGAAGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTA
ACCATCCATAAATATACGGGTACGGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAA
GCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCAGAAGCCAATACGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCG
CCAACGGCAAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAA
CCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGG
AACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACG
ATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(503-844)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

79.143

100

0.801

Multiple sequence alignment