Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ETT64_RS05230 Genome accession   NZ_CP035435
Coordinates   1007906..1008382 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain emm64.3     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1002906..1013382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT64_RS05215 (ETT64_05215) fbp54 1003719..1005371 (+) 1653 WP_030125975.1 Rqc2 family fibronectin-binding protein Fbp54 -
  ETT64_RS05220 (ETT64_05220) - 1005430..1006677 (-) 1248 WP_136292922.1 tetratricopeptide repeat protein -
  ETT64_RS05225 (ETT64_05225) - 1006667..1007848 (-) 1182 WP_002990002.1 AI-2E family transporter -
  ETT64_RS05230 (ETT64_05230) mutX 1007906..1008382 (-) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ETT64_RS05240 (ETT64_05240) speh 1008986..1009696 (-) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -
  ETT64_RS05245 (ETT64_05245) spei 1009722..1010399 (-) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  ETT64_RS05250 (ETT64_05250) - 1010668..1011873 (-) 1206 WP_136085564.1 glucosaminidase domain-containing protein -
  ETT64_RS05255 (ETT64_05255) - 1011984..1012169 (-) 186 WP_002990010.1 holin -
  ETT64_RS05260 (ETT64_05260) - 1012166..1012462 (-) 297 WP_002990012.1 hypothetical protein -
  ETT64_RS05265 (ETT64_05265) - 1012473..1013105 (-) 633 WP_136085563.1 hypothetical protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=301672 ETT64_RS05230 WP_002984880.1 1007906..1008382(-) (mutX) [Streptococcus pyogenes strain emm64.3]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=301672 ETT64_RS05230 WP_002984880.1 1007906..1008382(-) (mutX) [Streptococcus pyogenes strain emm64.3]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703