Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DRA68_RS00330 Genome accession   NZ_CP030823
Coordinates   64133..67249 (-) Length   1038 a.a.
NCBI ID   WP_196082896.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 14-627     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 59133..72249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DRA68_RS00315 (DRA68_00380) - 59803..60087 (+) 285 WP_002226617.1 DUF2523 domain-containing protein -
  DRA68_RS00320 (DRA68_00385) - 60088..61275 (+) 1188 Protein_60 zonular occludens toxin family protein -
  DRA68_RS00325 (DRA68_00390) - 61490..62446 (+) 957 WP_002212521.1 IS110-like element ISNgo3 family transposase -
  DRA68_RS00330 (DRA68_00410) pilC 64133..67249 (-) 3117 WP_196082896.1 PilC family type IV pilus tip adhesin Machinery gene
  DRA68_RS00335 (DRA68_00425) apbC 68203..69282 (-) 1080 WP_002248538.1 iron-sulfur cluster carrier protein ApbC -
  DRA68_RS00345 (DRA68_00435) - 69647..70156 (+) 510 WP_002224078.1 protein disulfide oxidoreductase -
  DRA68_RS00350 (DRA68_00445) nadR 70499..70939 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DRA68_RS00355 (DRA68_00450) hpaC 71054..71554 (+) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1038 a.a.        Molecular weight: 113442.31 Da        Isoelectric Point: 9.7038

>NTDB_id=301653 DRA68_RS00330 WP_196082896.1 64133..67249(-) (pilC) [Neisseria meningitidis strain 14-627]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAQAETHNYAIVMNEQNQLKVKQKDSYSTLREKDRERKFIYNKGWQGGGSV
LFDNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDANALKERNNAVDWIHTTRAGLAGYAYTNVICRSHQCPQLVYKTRFS
FDNPDLAKRGGGLDRHTEPSRDNSLIYKLKDHPWLGVSFNLGSENTVKNSQSSSRLISSFSEDNNNQTIVSTTENHPISL
GDGQREHTAVAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQRTGLGGLLGFHAKWDIKDTGQIPVELGLPQIK
AGRCINKPNPNPKAQALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSE
IKSKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGVDPDASEWKKVLLPWTVRASNDDNQFKTIN
QQLNQQKIQYSQRYRIRDNGNRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDND
TSALKDSTLAKELRTFAEKGYVGDRYGVDGGFVLRKVERNGKDHVFMFGAMGFGGRGAYALDLTKADGSDPTAVSLFDVK
NDNNGKNSNNSNNSVELGYTVGTPQIGKTHNGKYAAFLASGYATKDINNGDNKTALYVYDLESSGTLIKKIEVPNSKGGL
SSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSGQDPNQWSVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDVL
STDEQHIYGIFDDDTATTGSVNFSGLGGGLLEQELKQEGKTLFLTDYKRSDGSGNKGWVVKLKEGQRVTVKPTVVLRTAF
VTIHKYTGTDKCGAETAILGINTADGGKLTKKSARPIVPEANTAVAQYSGHKQTANGKSIPIGCMQKGNEIVCPNGYVYD
KPVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3117 bp        

>NTDB_id=301653 DRA68_RS00330 WP_196082896.1 64133..67249(-) (pilC) [Neisseria meningitidis strain 14-627]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGGGG
GGGGGGGGGGGCGCAGGCGGAAACCCATAACTACGCTATTGTCATGAACGAACAAAATCAGCTGAAGGTAAAGCAGAAGG
ATTCATATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGGCTGGCAGGGTGGAGGCTCTGTC
TTGTTCGACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTA
CGGCAAGGTTTCCGGTTTTGATGCCAACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCGGGCCG
GGCTGGCAGGCTACGCCTACACCAACGTCATATGCAGAAGCCACCAATGCCCCCAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGCAAAAAGAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCTCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCCAATCATCCA
GCAGATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAAACCACCCTATTTCCCTT
GGCGACGGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAA
AGATATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAGGACGGGGCTTGGCG
GCTTGCTAGGTTTTCATGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCGGTCGAGCTCGGCCTGCCGCAAATCAAA
GCAGGCCGCTGCATCAACAAACCGAACCCCAATCCCAAAGCCCAAGCCCTTTCGCCGGCACTGACTGCCCCCGCGCTGTG
GTTCGGACCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAA
TTTTCCTGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAG
ATTAAAAGTAAAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACAGCAGATTAAACTTCA
AGGCAATGAGGTCACTAGTTTTAATGTAAACAACGGCAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTG
ATGCCAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACAATCAATTTAAAACAATTAAC
CAACAACTTAACCAACAAAAAATCCAATACAGCCAAAGATACCGCATCCGCGACAACGGCAATCGCGATTTGGGCGACAT
CGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAA
GCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGAC
ACTTCCGCTCTCAAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGG
CGTGGACGGCGGCTTTGTCTTGCGCAAAGTCGAACGGAACGGGAAAGACCATGTGTTTATGTTCGGCGCGATGGGCTTTG
GCGGCAGAGGTGCATACGCCTTGGATTTGACCAAAGCCGACGGCAGTGACCCGACCGCCGTTTCCCTGTTTGATGTCAAA
AATGACAATAATGGCAAGAATAGCAATAATAGCAATAATAGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGG
CAAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGACATTAACAACGGCGACAATAAAA
CCGCGCTGTATGTATATGATTTGGAAAGCAGCGGCACGCTGATTAAAAAAATCGAAGTACCCAACAGCAAGGGCGGGCTT
TCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTA
CCGCTTTGATTTGAGCGGTCAAGATCCTAATCAATGGTCTGTACGCACCATTTTCAGCGGCAACAAACCGATTACTTCCG
CGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGTACGGGCAGTGATTTGAGTGAGGAGGATGTACTC
AGTACGGATGAACAACATATTTACGGTATCTTCGACGACGATACGGCGACGACGGGTAGTGTAAACTTCAGCGGTTTGGG
AGGCGGGCTGCTCGAGCAAGAGCTTAAGCAGGAGGGTAAAACCTTATTCCTGACCGATTATAAGCGATCCGACGGCTCGG
GCAATAAGGGGTGGGTAGTGAAGCTGAAGGAAGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTT
GTAACCATCCATAAATATACGGGTACGGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGG
CAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCAGAAGCCAATACGGCTGTCGCGCAATATTCCGGCCATAAGCAAA
CCGCCAACGGCAAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGAC
AAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAG
CGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGA
ACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(504-845)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

79.068

100

0.801

Multiple sequence alignment