Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DRA75_RS00280 Genome accession   NZ_CP030816
Coordinates   56310..59393 (-) Length   1027 a.a.
NCBI ID   WP_196083691.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 16-92     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 51310..64393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DRA75_RS00260 - 51681..51848 (-) 168 WP_153312129.1 hypothetical protein -
  DRA75_RS00265 (DRA75_00305) - 51852..52241 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  DRA75_RS00270 (DRA75_00320) - 52820..52957 (-) 138 WP_002214606.1 VOC family protein -
  DRA75_RS00275 (DRA75_00325) carA 53003..54136 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DRA75_RS00280 (DRA75_00355) pilC 56310..59393 (-) 3084 WP_196083691.1 PilC family type IV pilus tip adhesin Machinery gene
  DRA75_RS00285 (DRA75_00370) apbC 60347..61426 (-) 1080 WP_002248538.1 iron-sulfur cluster carrier protein ApbC -
  DRA75_RS00295 (DRA75_00380) - 61791..62300 (+) 510 WP_002224078.1 protein disulfide oxidoreductase -
  DRA75_RS00300 (DRA75_00390) nadR 62643..63083 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DRA75_RS00305 (DRA75_00395) hpaC 63198..63698 (+) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1027 a.a.        Molecular weight: 111991.90 Da        Isoelectric Point: 9.8356

>NTDB_id=301604 DRA75_RS00280 WP_196083691.1 56310..59393(-) (pilC) [Neisseria meningitidis strain 16-92]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAMAQTHKYAIIMNERKQPEVKSNVPSSIKDKDRKREYIHYKYKTGGGSVS
FNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDADALKERNNAAGWIRTTRIALAGYSYAGIHCGSVQGCPKLVYKTRFS
FDNPDLAKTGGGLDRHTEPSRDNSPIYKLKDYPWLGVSFNLGSENTVQNSKSSSKLISSFSENNNNQTIVSTTEGSPISL
GDQQREHTAVVYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQNTGFGLLNFWAKWDIKDNGQIPVKLGLTQVKA
GRCVNKNNPNPNAKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSRIYLQNLKRKTDPNKPGRYSLADLTKSDI
ESRQPGFTGRQTVIRLDSGVQQIKLQGNEVANFNGNDGKNDTFGIVSEGSFMPDTSEWKKVLLPWTVRGLDNDNQFKIFN
QEAKDNKPKYSQRYRIRDNNGNRNLGDIVNSPIVAVGEYLATSANDGMVHIFKKGNGDAHNYSLKLSYIPGTMPRKNIEN
NDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVEWKGQNRVFMFGAMGFGGRGAYALDLTKADSNNPTAVSLFDVKNDKN
SNNGVQLGYTVGTPQIGKTHDGKYAAFLASGYATKEITSNDNKTALYVYDLESNGTLIKKIEVPGGKGGLSSPTLVDKDL
DGTVDIAYAGDRGGKMYRFDLSGQSPDQWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDKTDEQYIYGI
FDDDTATTGPVNFSGTGGGLLEQVLTEENKTLFLTDYKRSDGSGSKGWVVKLKDGQRVTVKPTVVLRTAFVTIRKYKDNG
CGAETAILGINTADGGKLTKKSARPIVPEANQAVAQYSGHKKGTNGKSIPIGCMEKNGGTVCPNGYVYDKPVNVRYLDEK
KTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFF

Nucleotide


Download         Length: 3084 bp        

>NTDB_id=301604 DRA75_RS00280 WP_196083691.1 56310..59393(-) (pilC) [Neisseria meningitidis strain 16-92]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTCGAATG
TGCCATCTTCAATAAAGGACAAAGACAGGAAGCGCGAATATATTCATTATAAGTACAAAACAGGAGGAGGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCGCCGGTTGGATTCGTACCACCCGCATCGCGC
TGGCAGGCTACAGCTACGCCGGTATCCATTGCGGAAGTGTCCAAGGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGCAAAAACAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCCCATTTA
CAAATTGAAAGATTATCCATGGTTGGGGGTATCTTTCAATTTGGGCAGCGAGAATACCGTCCAAAATAGCAAATCATCCA
GCAAATTGATATCTTCTTTTAGTGAAAACAATAATAATCAAACCATCGTCTCTACGACAGAAGGCTCCCCTATTTCCCTT
GGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAA
AGATATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAATACGGGGTTTGGCT
TGCTAAATTTTTGGGCTAAGTGGGACATTAAAGATAACGGGCAGATTCCAGTCAAGCTCGGCCTGACGCAAGTCAAAGCA
GGCCGCTGCGTCAACAAAAATAACCCCAATCCCAATGCCAAAGCCCCCTCCCCCGCACTGACCGCCCCCGCGCTGTGGTT
CGGACCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCCGCATCT
ACCTTCAAAATCTGAAAAGAAAAACCGACCCCAACAAACCCGGTCGCTATTCTCTCGCAGACTTGACTAAGTCGGATATT
GAAAGTCGACAGCCGGGTTTCACAGGGCGGCAAACCGTCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTTCAAGG
CAATGAGGTCGCCAATTTTAATGGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAAGGGAGCTTCATGCCTG
ATACCAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTTTAGATAATGACAATCAATTTAAAATATTTAAC
CAAGAAGCAAAAGACAACAAGCCAAAATACAGTCAAAGATACCGCATCCGCGACAACAACGGCAATCGCAATTTGGGCGA
CATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAAA
AAGGCAACGGGGACGCGCACAACTATAGTCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAGAATATTGAAAAC
AACGACTCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGG
CTTTGTCTTGCGCCAAGTCGAATGGAAAGGGCAAAACCGCGTGTTTATGTTCGGCGCGATGGGCTTTGGCGGCAGAGGCG
CGTATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAATGACAAGAAT
AGCAATAACGGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACGACGGCAAATACGCCGCCTT
CCTCGCCTCCGGTTATGCGACTAAAGAGATTACCAGCAACGATAATAAAACCGCGCTGTATGTGTATGATTTGGAAAGCA
ACGGTACGCTGATTAAAAAAATCGAAGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTG
GACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAAAATGTACCGCTTTGATTTGAGCGGTCAAAGTCCTGA
TCAATGGACTGTACGCCCTATTTTTGAAGGCACGAAGCCGATTACTTCCGCGCCCGCTATTTCCCAACTGAAAGACAAAC
GCGTGGTCATCTTCGGCACGGGCAGCGATTTGAGTGAGGATGATGTTGATAAAACGGACGAACAATATATTTACGGTATC
TTTGACGACGATACGGCGACGACGGGTCCTGTAAACTTCAGCGGTACGGGAGGCGGGCTGCTCGAGCAAGTGCTTACTGA
GGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCGACGGCTCGGGCAGCAAAGGGTGGGTAGTGAAATTGAAGG
ACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATAAAGACAACGGC
TGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGT
GCCGGAAGCCAATCAGGCTGTCGCGCAATATTCCGGTCATAAGAAAGGCACCAACGGCAAATCCATCCCTATAGGTTGTA
TGGAAAAAAACGGGGGAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAG
AAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAA
AAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGA
CGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(505-835)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

80.692

100

0.818

Multiple sequence alignment