Detailed information NTG0301487

Bioinformatically predicted

Overview

• Name: rexA
• Type: Machinery gene
• Locus tag: ETT66_RS06255
• Genome accession: NZ_CP035433
• Coordinates: 1234661..1238290 (-)
• Length: 1209 a.a.
• NCBI ID: WP_315940873.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm65
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1229661..1243290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT66_RS06230 (ETT66_06235)	rpoD	1229838..1230947 (-)	1110	WP_002985187.1	RNA polymerase sigma factor RpoD	-
ETT66_RS06235 (ETT66_06240)	dnaG	1230956..1232770 (-)	1815	WP_111689608.1	DNA primase	-
ETT66_RS06240 (ETT66_06245)	mscL	1232901..1233263 (+)	363	WP_002990299.1	large conductance mechanosensitive channel protein MscL	-
ETT66_RS06245 (ETT66_06250)	rpsU	1233392..1233568 (-)	177	WP_000048058.1	30S ribosomal protein S21	-
ETT66_RS06250 (ETT66_06255)	-	1233709..1234521 (-)	813	WP_136286224.1	transporter substrate-binding domain-containing protein	-
ETT66_RS06255 (ETT66_06260)	rexA	1234661..1238290 (-)	3630	WP_315940873.1	helicase-exonuclease AddAB subunit AddA	Machinery gene
ETT66_RS06260 (ETT66_06265)	rexB	1238290..1241505 (-)	3216	WP_136286223.1	ATP-dependent nuclease subunit B	Machinery gene
ETT66_RS06265 (ETT66_06270)	-	1241656..1242558 (+)	903	WP_110002816.1	neutral zinc metallopeptidase	-

Sequence

Protein

• Length: 1209 a.a.
• Molecular weight: 138923.98 Da
• Isoelectric Point: 6.5209

>NTDB_id=301487 ETT66_RS06255 WP_315940873.1 1234661..1238290(-) (rexA) [Streptococcus pyogenes strain emm65]
MSFAPFLSPEAIKHLQENERYSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFT
VKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVLK
QEVFSKLFSEFMNQKEAPAFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDI
ELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTDLIPSGNDVT
VSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAHFAIKILEENTDIR
QSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFR
SQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSYTQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKE
IIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRSP
MFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAYPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFND
RFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQF
PYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVA
MTRAEKKVYFIGKASKSKSQDITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQ
TPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEPLLEPIGVDIIEKSSRSLSDFTLP
HFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYRE
APFAILKVDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMG
GGKPEIVEV

Nucleotide

• Length: 3630 bp

>NTDB_id=301487 ETT66_RS06255 WP_315940873.1 1234661..1238290(-) (rexA) [Streptococcus pyogenes strain emm65]
ATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTACAGTGATCAGTCTCAAAA
ACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAAAAA
CCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTTACT
GTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCAAAT
GAAAGTTTATTTAACAGAACAATTGCAATCTCTTTGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAGTAG
TAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTAAAG
CAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAATCAAAAAGAGGCACCGGCGTTTAGGGCTCTTGTGAAAAATTT
TTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAAATC
CAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGACTTGAAGATATCCCGGATCATGATATT
GAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCTGAC
TAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATTTTA
AATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGACCTTATACCATCTGGGAATGATGTTACA
GTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAACTAAAACAATTTAGGCATTTAGAAACAATTTTAAT
GTATCAGAAAGACTGTTTTCCCTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTGTCA
AAATACAAGAAAGTGCTTTTGAATTTTCAGATATTGCACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATTCGC
CAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCTGAC
CTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATCCTC
AGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTTCGT
AGCCAATCAGAGGTGTTAAATGTCAGCAACGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATATGA
TGAGCAACATCAGTTAATAGCAGGTAGTTATACTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTATATA
ATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGTGAGGTTACAATTGTTGCCAAAGAA
ATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGATAT
CATTTCTCATACATTCAATCAATATGGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTGAAG
TGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCACCG
ATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATATGA
CAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTTATCCTGAATTGATTCACGATACCTTGCTTGGCAAGTTAAATGTTT
TTTTAAAGACGTTGAAAAGCTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTCAATGAT
CGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACGTGC
TAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAAATG
ACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACTATTCACAAGTCTAAAGGTTTACAATTT
CCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCAGCA
CGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCATGG
AAACCTTACCTTATCAATTGAACAAACAAGAATTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTACTGTATGTTGCT
ATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGATATCACAGATCCTAAAAA
GTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATATAT
TTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTTCAA
ACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTTAGA
AGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACTCCTAGCCAACTTAAGGCAA
CTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTGCCA
CATTTTTCAAAAAAAGCAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTTGTC
AAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGGAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTGATC
TCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGAGAA
GCGCCATTTGCTATTTTAAAAGTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTTTTT
GTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACCAAC
AACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATGGGA
GGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

• UvrD-like helicase C-terminal domain (UvrD_C) (473-891)

• PD-(D/E)XK nuclease superfamily (PDDEXK_1) (1045-1196)

• UvrD/REP helicase N-terminal domain (UvrD-helicase) (29-463)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rexA	Streptococcus pneumoniae R6	48.453	100	0.492