Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT67_RS05760 Genome accession   NZ_CP035432
Coordinates   1132529..1133191 (-) Length   220 a.a.
NCBI ID   WP_136019785.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm11     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1127529..1138191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT67_RS05740 (ETT67_05730) - 1128143..1128325 (-) 183 WP_023078840.1 hypothetical protein -
  ETT67_RS05745 (ETT67_05735) sodA 1128492..1129097 (-) 606 WP_023078860.1 superoxide dismutase SodA -
  ETT67_RS05750 (ETT67_05740) holA 1129194..1130234 (-) 1041 WP_023078852.1 DNA polymerase III subunit delta -
  ETT67_RS05755 (ETT67_05745) comEC/celB 1130305..1132548 (-) 2244 WP_115224604.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT67_RS05760 (ETT67_05750) comEA/celA/cilE 1132529..1133191 (-) 663 WP_136019785.1 ComEA family DNA-binding protein Machinery gene
  ETT67_RS05765 (ETT67_05755) - 1133391..1134131 (-) 741 WP_021299345.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT67_RS05770 (ETT67_05760) - 1134249..1135025 (+) 777 WP_023078849.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT67_RS05775 (ETT67_05765) - 1135015..1135293 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  ETT67_RS05780 (ETT67_05770) - 1135317..1137317 (-) 2001 WP_030126409.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24642.50 Da        Isoelectric Point: 7.2090

>NTDB_id=301383 ETT67_RS05760 WP_136019785.1 1132529..1133191(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm11]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKRAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=301383 ETT67_RS05760 WP_136019785.1 1132529..1133191(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm11]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACGTGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(156-217)

SLBB domain (SLBB)

(77-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405