Detailed information NTG0301137

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ETT70_RS08790
• Genome accession: NZ_CP035429
• Coordinates: 1712601..1713368 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emmNA
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1707601..1718368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT70_RS08775 (ETT70_08765)	hexB	1708059..1710041 (-)	1983	WP_136076690.1	DNA mismatch repair endonuclease MutL	Machinery gene
ETT70_RS08780 (ETT70_08770)	-	1710136..1711281 (-)	1146	WP_021299091.1	site-specific integrase	-
ETT70_RS08785 (ETT70_08775)	-	1711609..1711752 (+)	144	WP_002992192.1	putative holin-like toxin	-
ETT70_RS08790 (ETT70_08780)	irvR	1712601..1713368 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
ETT70_RS08795 (ETT70_08785)	-	1713522..1713728 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
ETT70_RS08800 (ETT70_08790)	-	1713762..1713962 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
ETT70_RS08805 (ETT70_08795)	-	1713983..1714390 (+)	408	WP_002992501.1	hypothetical protein	-
ETT70_RS09435	-	1714403..1714525 (+)	123	WP_002992500.1	hypothetical protein	-
ETT70_RS08810 (ETT70_08800)	-	1714806..1715327 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
ETT70_RS08815 (ETT70_08805)	-	1715572..1715904 (+)	333	WP_002992497.1	hypothetical protein	-
ETT70_RS08820 (ETT70_08810)	-	1715904..1716095 (+)	192	WP_080032246.1	hypothetical protein	-
ETT70_RS08825 (ETT70_08815)	-	1716107..1716469 (+)	363	WP_136118488.1	hypothetical protein	-
ETT70_RS08830 (ETT70_08820)	-	1716466..1716795 (+)	330	WP_000174505.1	hypothetical protein	-
ETT70_RS08835 (ETT70_08825)	-	1716798..1717070 (+)	273	WP_001100459.1	hypothetical protein	-
ETT70_RS08840 (ETT70_08830)	-	1717071..1717928 (+)	858	WP_002992489.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=301137 ETT70_RS08790 WP_003058809.1 1712601..1713368(-) (irvR) [Streptococcus pyogenes strain emmNA]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=301137 ETT70_RS08790 WP_003058809.1 1712601..1713368(-) (irvR) [Streptococcus pyogenes strain emmNA]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4