Detailed information NTG0301108

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DNH96_RS03680
• Genome accession: NZ_CP030715
• Coordinates: 719245..720288 (-)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain VB88
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 714245..725288

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DNH96_RS03650 (DNH96_03635)	-	714802..715005 (-)	204	WP_014613487.1	DUF1128 family protein	-
DNH96_RS03655 (DNH96_03640)	-	715139..715597 (+)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
DNH96_RS03660 (DNH96_03645)	-	715605..715892 (+)	288	WP_014613485.1	YtxH domain-containing protein	-
DNH96_RS03665 (DNH96_03650)	-	716108..717445 (+)	1338	WP_015729387.1	YihY/virulence factor BrkB family protein	-
DNH96_RS03670 (DNH96_03655)	-	717478..718059 (+)	582	WP_070407816.1	carbonic anhydrase	-
DNH96_RS03675 (DNH96_03660)	vraR	718626..719255 (-)	630	WP_014613482.1	response regulator transcription factor	Regulator
DNH96_RS03680 (DNH96_03665)	vraS	719245..720288 (-)	1044	WP_014613481.1	sensor histidine kinase	Regulator
DNH96_RS03685 (DNH96_03670)	liaF	720285..720986 (-)	702	WP_096533561.1	cell wall-active antibiotics response protein LiaF	-
DNH96_RS03690 (DNH96_03675)	-	720999..721388 (-)	390	WP_014613479.1	hypothetical protein	-
DNH96_RS03695 (DNH96_03680)	map	721486..722247 (-)	762	WP_014613478.1	type I methionyl aminopeptidase	-
DNH96_RS03700 (DNH96_03685)	-	722344..723342 (+)	999	WP_014613477.1	aromatic acid exporter family protein	-
DNH96_RS03705 (DNH96_03690)	-	724311..725033 (-)	723	WP_014613476.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=301108 DNH96_RS03680 WP_014613481.1 719245..720288(-) (vraS) [Staphylococcus pseudintermedius strain VB88]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=301108 DNH96_RS03680 WP_014613481.1 719245..720288(-) (vraS) [Staphylococcus pseudintermedius strain VB88]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGAATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839