Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ETT70_RS04145 Genome accession   NZ_CP035429
Coordinates   773859..774335 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain emmNA     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 768859..779335
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT70_RS04115 (ETT70_04105) - 769691..770119 (+) 429 WP_063629045.1 DUF1617 family protein -
  ETT70_RS04120 (ETT70_04110) - 770122..770754 (+) 633 WP_063629046.1 hypothetical protein -
  ETT70_RS04125 (ETT70_04115) - 770765..771064 (+) 300 WP_002993162.1 hypothetical protein -
  ETT70_RS04130 (ETT70_04120) - 771061..771246 (+) 186 WP_111676573.1 holin -
  ETT70_RS04135 (ETT70_04125) - 771357..772559 (+) 1203 WP_136275815.1 glucosaminidase domain-containing protein -
  ETT70_RS04140 (ETT70_04130) prx 773263..773451 (+) 189 WP_136105726.1 Paratox Regulator
  ETT70_RS04145 (ETT70_04135) mutX 773859..774335 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ETT70_RS04150 (ETT70_04140) - 774393..775574 (+) 1182 WP_011284730.1 AI-2E family transporter -
  ETT70_RS04155 (ETT70_04145) - 775564..776811 (+) 1248 WP_136275816.1 tetratricopeptide repeat protein -
  ETT70_RS04160 (ETT70_04150) fbp54 776870..778522 (-) 1653 WP_136275817.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=301089 ETT70_RS04145 WP_002984880.1 773859..774335(+) (mutX) [Streptococcus pyogenes strain emmNA]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=301089 ETT70_RS04145 WP_002984880.1 773859..774335(+) (mutX) [Streptococcus pyogenes strain emmNA]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTATTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment