Detailed information NTG0301086

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ETT70_RS03650
• Genome accession: NZ_CP035429
• Coordinates: 696000..698099 (-)
• Length: 699 a.a.
• NCBI ID: WP_002984939.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emmNA
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 691000..703099

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT70_RS03620 (ETT70_03610)	-	691477..692316 (+)	840	WP_010922172.1	thymidylate synthase	-
ETT70_RS03625 (ETT70_03615)	-	692396..692893 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT70_RS03630 (ETT70_03620)	-	692913..693083 (+)	171	WP_002984950.1	hypothetical protein	-
ETT70_RS03635 (ETT70_03625)	clpX	693213..694442 (+)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT70_RS03640 (ETT70_03630)	yihA	694452..695051 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT70_RS03645 (ETT70_03635)	-	695199..695942 (+)	744	WP_002984942.1	hypothetical protein	-
ETT70_RS03650 (ETT70_03640)	clpC	696000..698099 (-)	2100	WP_002984939.1	AAA family ATPase	Regulator
ETT70_RS03655 (ETT70_03645)	rpiA	698477..699160 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-
ETT70_RS03660 (ETT70_03650)	-	699237..700448 (+)	1212	WP_002984934.1	phosphopentomutase	-
ETT70_RS03665 (ETT70_03655)	arsC	700467..700907 (+)	441	WP_002984932.1	arsenate reductase (glutaredoxin)	-
ETT70_RS03670 (ETT70_03660)	-	700891..701700 (+)	810	WP_038432917.1	purine-nucleoside phosphorylase	-
ETT70_RS03675 (ETT70_03665)	deoD	702363..703076 (+)	714	WP_002990147.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77330.35 Da
• Isoelectric Point: 5.5562

>NTDB_id=301086 ETT70_RS03650 WP_002984939.1 696000..698099(-) (clpC) [Streptococcus pyogenes strain emmNA]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQNDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=301086 ETT70_RS03650 WP_002984939.1 696000..698099(-) (clpC) [Streptococcus pyogenes strain emmNA]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACCCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTCGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TCAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• AAA lid domain (AAA_lid_9) (259-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.084	100	0.474
clpE	Streptococcus mutans UA159	49.224	92.132	0.454
clpE	Streptococcus pneumoniae TIGR4	49.438	89.127	0.441
clpE	Streptococcus pneumoniae Rx1	49.438	89.127	0.441
clpE	Streptococcus pneumoniae D39	49.438	89.127	0.441
clpE	Streptococcus pneumoniae R6	49.438	89.127	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	44.662	95.136	0.425
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.871	93.276	0.391
clpC	Streptococcus pneumoniae D39	41.871	93.276	0.391
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus thermophilus LMG 18311	42.587	90.701	0.386
clpC	Streptococcus pneumoniae TIGR4	42.857	90.129	0.386
clpC	Streptococcus mutans UA159	41.719	91.559	0.382