Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   SPT_RS00295 Genome accession   NC_012469
Coordinates   42067..42303 (+) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae Taiwan19F-14     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 37067..47303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPT_RS11295 - 40760..40969 (+) 210 Protein_47 transposase -
  SPT_RS11300 - 41004..41801 (-) 798 Protein_48 transposase -
  SPT_RS00295 (SPT_0058) comW 42067..42303 (+) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  SPT_RS00300 (SPT_0059) - 42534..43820 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  SPT_RS00305 (SPT_0060) tadA 44021..44488 (+) 468 WP_000291879.1 tRNA adenosine(34) deaminase TadA -
  SPT_RS00310 (SPT_0061) - 44675..45118 (+) 444 WP_000701992.1 dUTP diphosphatase -
  SPT_RS00315 (SPT_0062) - 45120..45635 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  SPT_RS00320 (SPT_0063) radA 45649..47010 (+) 1362 WP_073076903.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=30091 SPT_RS00295 WP_000939544.1 42067..42303(+) (comW) [Streptococcus pneumoniae Taiwan19F-14]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=30091 SPT_RS00295 WP_000939544.1 42067..42303(+) (comW) [Streptococcus pneumoniae Taiwan19F-14]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974

  comW Streptococcus pneumoniae D39

97.436

100

0.974

  comW Streptococcus pneumoniae R6

97.436

100

0.974

  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974

  comW Streptococcus mitis SK321

78.205

100

0.782

  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769


Multiple sequence alignment