Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ETT72_RS04505 Genome accession   NZ_CP035427
Coordinates   837188..837664 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain emm74     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 832188..842664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT72_RS04480 (ETT72_04475) - 832229..833017 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  ETT72_RS04485 (ETT72_04480) - 833057..834163 (+) 1107 WP_032464329.1 FAD-binding oxidoreductase -
  ETT72_RS04490 (ETT72_04485) rfbA 834221..835090 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  ETT72_RS04495 (ETT72_04490) - 835090..835683 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ETT72_RS04500 (ETT72_04495) rfbB 835927..836967 (+) 1041 WP_023612000.1 dTDP-glucose 4,6-dehydratase -
  ETT72_RS04505 (ETT72_04500) mutX 837188..837664 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ETT72_RS04510 (ETT72_04505) - 837722..838903 (+) 1182 WP_002984879.1 AI-2E family transporter -
  ETT72_RS04515 (ETT72_04510) - 838893..840140 (+) 1248 WP_032464330.1 tetratricopeptide repeat protein -
  ETT72_RS04520 (ETT72_04515) fbp54 840199..841851 (-) 1653 WP_032464331.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=300897 ETT72_RS04505 WP_002984880.1 837188..837664(+) (mutX) [Streptococcus pyogenes strain emm74]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=300897 ETT72_RS04505 WP_002984880.1 837188..837664(+) (mutX) [Streptococcus pyogenes strain emm74]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703