Detailed information NTG0300861

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSC59_RS15015
• Genome accession: NZ_CP030326
• Coordinates: 2804206..2805093 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AR_474
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2799206..2810093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC59_RS14980	-	2799225..2799317 (+)	93	WP_010956583.1	hypothetical protein	-
CSC59_RS14985 (CSC59_2481)	-	2799425..2799922 (-)	498	WP_001065268.1	glutathione peroxidase	-
CSC59_RS14990	-	2799932..2800192 (-)	261	WP_001791974.1	hypothetical protein	-
CSC59_RS15000	-	2800574..2800687 (-)	114	Protein_2762	hypothetical protein	-
CSC59_RS15005 (CSC59_2483)	-	2801346..2803346 (-)	2001	WP_000776750.1	ABC transporter permease	-
CSC59_RS15010 (CSC59_2484)	-	2803343..2804098 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSC59_RS15015 (CSC59_2485)	braS	2804206..2805093 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSC59_RS15020 (CSC59_2486)	braR	2805104..2805769 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSC59_RS15025 (CSC59_2487)	-	2805795..2805995 (-)	201	WP_000604730.1	hypothetical protein	-
CSC59_RS15030 (CSC59_2488)	-	2806193..2807617 (+)	1425	WP_000953755.1	alkaline phosphatase	-
CSC59_RS15510	-	2807687..2807797 (+)	111	Protein_2769	hypothetical protein	-
CSC59_RS15040 (CSC59_2489)	-	2807900..2808355 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSC59_RS15045 (CSC59_2490)	-	2808600..2809361 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=300861 CSC59_RS15015 WP_000143425.1 2804206..2805093(-) (braS) [Staphylococcus aureus strain AR_474]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=300861 CSC59_RS15015 WP_000143425.1 2804206..2805093(-) (braS) [Staphylococcus aureus strain AR_474]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1