Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CSC60_RS06180 Genome accession   NZ_CP030323
Coordinates   1234884..1235600 (-) Length   238 a.a.
NCBI ID   WP_063663582.1    Uniprot ID   D5LFT2
Organism   Staphylococcus aureus strain AR_475     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1229884..1240600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC60_RS06160 (CSC60_1134) - 1230978..1231928 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  CSC60_RS06165 (CSC60_1135) - 1232077..1233561 (+) 1485 WP_000141422.1 sucrose-6-phosphate hydrolase -
  CSC60_RS06170 (CSC60_1136) - 1233558..1234517 (+) 960 WP_001253300.1 carbohydrate kinase -
  CSC60_RS06175 - 1234705..1234812 (-) 108 WP_031844951.1 hypothetical protein -
  CSC60_RS06180 (CSC60_1137) agrA 1234884..1235600 (-) 717 WP_063663582.1 LytTR family DNA-binding domain-containing protein Regulator
  CSC60_RS06185 - 1235619..1236911 (-) 1293 WP_031844950.1 GHKL domain-containing protein -
  CSC60_RS06190 (CSC60_1139) - 1236936..1237076 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  CSC60_RS06195 (CSC60_1140) agrB 1237073..1237642 (-) 570 WP_001105712.1 accessory gene regulator AgrB -
  CSC60_RS14630 (CSC60_1141) - 1237878..1238012 (+) 135 WP_001823225.1 delta-lysin family phenol-soluble modulin -
  CSC60_RS06205 (CSC60_1142) - 1238611..1239396 (-) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  CSC60_RS06210 (CSC60_1143) - 1239757..1240383 (-) 627 WP_000522383.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27847.86 Da        Isoelectric Point: 6.3001

>NTDB_id=300785 CSC60_RS06180 WP_063663582.1 1234884..1235600(-) (agrA) [Staphylococcus aureus strain AR_475]
MKIFICEGDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=300785 CSC60_RS06180 WP_063663582.1 1234884..1235600(-) (agrA) [Staphylococcus aureus strain AR_475]
ATGAAAATTTTCATTTGCGAAGGCGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D5LFT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment