Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SP70585_RS06080 Genome accession   NC_012468
Coordinates   1131927..1132391 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae 70585     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1126927..1137391
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS06060 (SP70585_1216) - 1127878..1128846 (-) 969 WP_000105362.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  SP70585_RS06065 (SP70585_1217) pdrM 1129000..1130361 (-) 1362 WP_000278546.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  SP70585_RS06070 - 1130372..1130632 (-) 261 WP_001105925.1 hypothetical protein -
  SP70585_RS06075 (SP70585_1218) - 1130646..1131914 (-) 1269 WP_000924499.1 dihydroorotase -
  SP70585_RS06080 (SP70585_1219) mutX 1131927..1132391 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  SP70585_RS06085 (SP70585_1220) - 1132401..1133054 (-) 654 WP_001809694.1 uracil-DNA glycosylase -
  SP70585_RS06090 - 1133192..1133794 (-) 603 WP_041170965.1 hypothetical protein -
  SP70585_RS06095 (SP70585_1222) - 1133828..1134541 (-) 714 WP_000120616.1 YjjG family noncanonical pyrimidine nucleotidase -
  SP70585_RS06100 (SP70585_1223) - 1134602..1135540 (-) 939 WP_012677149.1 FRG domain-containing protein -
  SP70585_RS06105 (SP70585_1224) - 1135705..1135908 (-) 204 Protein_1165 transposase -
  SP70585_RS06110 (SP70585_1225) - 1135993..1136367 (-) 375 WP_000213830.1 phospholipase D-like domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=30016 SP70585_RS06080 WP_001135768.1 1131927..1132391(-) (mutX) [Streptococcus pneumoniae 70585]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=30016 SP70585_RS06080 WP_001135768.1 1131927..1132391(-) (mutX) [Streptococcus pneumoniae 70585]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCTAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment