Detailed information NTG0300159

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ETK61_RS00585
• Genome accession: NZ_CP035406
• Coordinates: 106989..108071 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain SRCM103612
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 101989..113071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETK61_RS00570 (ETK61_00570)	mcsB	101997..103088 (+)	1092	WP_003235007.1	protein arginine kinase	-
ETK61_RS00575 (ETK61_00575)	clpC	103085..105517 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
ETK61_RS00580 (ETK61_00580)	radA/sms	105609..106985 (+)	1377	WP_003242044.1	DNA repair protein RadA	Machinery gene
ETK61_RS00585 (ETK61_00585)	disA	106989..108071 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ETK61_RS00590 (ETK61_00590)	yacL	108187..109287 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
ETK61_RS00595 (ETK61_00595)	ispD	109302..110000 (+)	699	WP_003235019.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ETK61_RS00600 (ETK61_00600)	ispF	109993..110469 (+)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
ETK61_RS00605 (ETK61_00605)	gltX	110560..112011 (+)	1452	WP_004399675.1	glutamate--tRNA ligase	-
ETK61_RS00615 (ETK61_00615)	cysE	112313..112966 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=300159 ETK61_RS00585 WP_003225736.1 106989..108071(+) (disA) [Bacillus subtilis strain SRCM103612]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=300159 ETK61_RS00585 WP_003225736.1 106989..108071(+) (disA) [Bacillus subtilis strain SRCM103612]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCTGGTCAAAAGATCCTATACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCCATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCTGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1