Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   SPH_RS06490 Genome accession   NC_010380
Coordinates   1240613..1241422 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1235613..1246422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS06470 (SPH_1335) - 1237970..1238956 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  SPH_RS06475 (SPH_1336) - 1239204..1239977 (-) 774 WP_000731136.1 ion transporter -
  SPH_RS06480 (SPH_1337) - 1240024..1240278 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  SPH_RS06485 (SPH_1338) - 1240280..1240522 (-) 243 WP_000208080.1 DUF6290 family protein -
  SPH_RS06490 (SPH_1339) vicX 1240613..1241422 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  SPH_RS06495 (SPH_1340) micB 1241424..1242773 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SPH_RS06500 (SPH_1341) micA 1242766..1243470 (-) 705 WP_000722076.1 response regulator YycF Regulator
  SPH_RS06505 (SPH_1342) mutY 1243525..1244700 (-) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  SPH_RS14245 - 1244797..1244922 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=30011 SPH_RS06490 WP_001289493.1 1240613..1241422(-) (vicX) [Streptococcus pneumoniae Hungary19A-6]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=30011 SPH_RS06490 WP_001289493.1 1240613..1241422(-) (vicX) [Streptococcus pneumoniae Hungary19A-6]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment