Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ETK49_RS09880 Genome accession   NZ_CP035405
Coordinates   1911160..1913070 (+) Length   636 a.a.
NCBI ID   WP_003181972.1    Uniprot ID   Q65JE1
Organism   Bacillus licheniformis strain SRCM103608     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1906160..1918070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETK49_RS09865 (ETK49_09865) ymcA 1907200..1907631 (+) 432 WP_003181967.1 RicAFT regulatory complex protein RicA family protein Regulator
  ETK49_RS09870 (ETK49_09870) cotE 1907874..1908422 (+) 549 WP_003181968.1 outer spore coat protein CotE -
  ETK49_RS09875 (ETK49_09875) hexA 1908533..1911142 (+) 2610 WP_011197985.1 DNA mismatch repair protein MutS Machinery gene
  ETK49_RS09880 (ETK49_09880) hexB 1911160..1913070 (+) 1911 WP_003181972.1 DNA mismatch repair endonuclease MutL Machinery gene
  ETK49_RS09885 (ETK49_09885) - 1913404..1913685 (+) 282 WP_003181975.1 putative quinol monooxygenase -
  ETK49_RS09890 (ETK49_09890) - 1913867..1914394 (+) 528 WP_003181977.1 pre-toxin TG domain-containing protein -
  ETK49_RS09895 (ETK49_09895) - 1914391..1914639 (+) 249 WP_080508521.1 HNH/endonuclease VII fold putative polymorphic toxin -
  ETK49_RS09900 (ETK49_09900) - 1914695..1915132 (+) 438 WP_011201654.1 hypothetical protein -
  ETK49_RS09910 (ETK49_09910) - 1916423..1916773 (+) 351 WP_241687608.1 hypothetical protein -
  ETK49_RS09915 (ETK49_09915) - 1916925..1917917 (-) 993 WP_003181980.1 GTP-binding protein -

Sequence

Protein


Download         Length: 636 a.a.        Molecular weight: 71389.32 Da        Isoelectric Point: 5.2899

>NTDB_id=300074 ETK49_RS09880 WP_003181972.1 1911160..1913070(+) (hexB) [Bacillus licheniformis strain SRCM103608]
MAKIVQLPDDLSNKIAAGEVVERPASVVKELVENAIDANSSVIEIDVEEAGLASIKVLDDGEGMDAEDCRTAFLRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLSIKTSTGEGAGTHLTLQGGRIISEQKAPSRRGTEITVTNLFFNTPARLKYM
KTIHTELGNITDVVNRIALAHPEVSIRLRHQGKTLLQTNGNGDVRHVLAAIYGTAVAKKMLPLEARSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAIHEGYHTLLPIGRHPITFIEINMDPLLVDVNVHPSKLEVRLSKETELHELIRDA
IKDVFKQQQLIPSVQVPKKTAPLINKPEQQKLDFDQVREPAPLSDSDVEREYKPEPSFSAMKLSSLVKDPPPSAPVEREE
NVMQDTEPEWPGAEEYTPEAAPAVQAEPEQAGENVQDEETPKERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIK
YEYFREKVGEVESEVQDLLVPLTFHYSKNEALTIDQHLDDLAKVGVFLESFGAGSYIVRCHPTWFPKGEETTIIEDIIQQ
VLDDRTIDIKKLREEAAIMMSCKGSIKANHHLRDDEITALLDELRRTSDPFTCPHGRPIIIHYSTYEMEKMFKRVM

Nucleotide


Download         Length: 1911 bp        

>NTDB_id=300074 ETK49_RS09880 WP_003181972.1 1911160..1913070(+) (hexB) [Bacillus licheniformis strain SRCM103608]
TTGGCAAAAATTGTTCAGCTGCCTGACGATTTATCGAATAAAATCGCGGCGGGTGAAGTAGTGGAAAGGCCGGCGTCGGT
CGTCAAAGAGCTTGTCGAAAATGCAATCGATGCGAACAGCTCCGTGATTGAAATCGATGTTGAAGAAGCGGGTCTCGCCT
CGATTAAAGTGCTTGACGACGGCGAAGGGATGGACGCAGAAGACTGCAGAACGGCTTTTTTGCGTCATGCCACAAGCAAA
ATCAAAGACGAAAACGACCTGTTTCGCGTCAGAACGCTCGGATTTCGCGGAGAAGCTTTGCCAAGTATCGCGTCTGTCTC
ACACTTAAGCATTAAAACGAGCACCGGAGAAGGGGCAGGCACCCATTTGACGCTGCAGGGGGGAAGAATCATTTCCGAGC
AAAAAGCGCCAAGCCGCAGAGGAACCGAAATTACGGTTACCAACCTGTTTTTCAATACGCCGGCAAGGCTGAAATACATG
AAAACGATTCATACCGAGCTTGGCAACATCACAGATGTGGTCAACAGAATCGCCCTTGCCCATCCGGAAGTTTCGATCAG
GCTGCGTCATCAAGGGAAAACGCTTCTGCAGACAAACGGAAACGGCGATGTCCGCCACGTGCTTGCGGCGATTTACGGCA
CGGCGGTTGCCAAAAAAATGCTCCCGCTTGAAGCGAGATCTCTTGACTTTGAAGTGAAGGGCTATATCGCTCTTCCTGAA
ATTACGCGCGCCTCGCGAAATTACATGTCATCTGTCGTCAACGGCAGATACATTAAAAACTTCCCGCTCGTAAAAGCGAT
CCACGAGGGCTACCATACGCTTCTTCCGATCGGCCGCCATCCGATCACGTTCATTGAAATCAACATGGACCCGCTCCTTG
TGGACGTCAACGTGCACCCGTCAAAGCTGGAGGTCAGGCTGAGCAAAGAGACGGAGCTTCACGAGCTGATTCGCGACGCC
ATCAAAGACGTCTTTAAACAGCAGCAGCTCATTCCAAGCGTGCAGGTCCCGAAAAAAACCGCACCTCTGATCAATAAACC
AGAGCAGCAAAAGCTTGATTTCGACCAGGTACGAGAACCGGCACCTCTTTCTGATTCTGATGTTGAAAGAGAGTATAAGC
CGGAGCCTTCGTTTTCGGCGATGAAATTAAGCTCGCTTGTCAAAGACCCGCCGCCTTCCGCTCCCGTAGAGCGCGAAGAA
AACGTAATGCAGGACACCGAGCCTGAATGGCCCGGAGCTGAAGAGTATACGCCTGAAGCCGCGCCGGCCGTACAAGCAGA
ACCGGAACAGGCAGGAGAGAACGTCCAGGACGAAGAGACGCCAAAAGAAAGGGTGCCGATCATGTATCCGATCGGCCAAA
TGCACGGCACCTACATACTTGCCCAAAATGAAAACGGGCTGTACATCATCGATCAGCACGCCGCACAGGAGCGGATCAAA
TACGAATATTTCCGTGAAAAAGTCGGGGAAGTCGAATCGGAAGTCCAGGACCTGCTTGTGCCGCTGACATTCCATTATTC
AAAAAATGAAGCGCTGACGATCGACCAGCACTTGGACGATTTAGCCAAAGTCGGCGTCTTTCTCGAATCGTTCGGCGCCG
GCAGCTATATCGTCCGATGCCACCCGACATGGTTTCCGAAAGGGGAAGAAACGACGATCATTGAAGACATCATTCAGCAG
GTCCTTGATGACCGCACGATCGACATCAAAAAACTGCGCGAAGAAGCCGCAATCATGATGAGCTGCAAAGGCTCCATCAA
AGCCAATCATCACCTGCGGGACGACGAAATCACCGCCCTGCTCGATGAGCTGCGCAGAACATCCGACCCTTTCACATGCC
CGCACGGCCGGCCGATCATCATCCACTACTCCACCTATGAGATGGAGAAGATGTTTAAGCGGGTAATGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)

MutL C terminal dimerisation domain (MutL_C)

(451-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65JE1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.859

100

0.47