Detailed information NTG0300015

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ETK49_RS00610
• Genome accession: NZ_CP035405
• Coordinates: 111823..112899 (+)
• Length: 358 a.a.
• NCBI ID: WP_003178277.1
• Uniprot ID: Q65PD4
• Organism: Bacillus licheniformis strain SRCM103608
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 106823..117899

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETK49_RS00595 (ETK49_00595)	-	106840..107931 (+)	1092	WP_003178273.1	protein arginine kinase	-
ETK49_RS00600 (ETK49_00600)	clpC	107928..110360 (+)	2433	WP_003178275.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
ETK49_RS00605 (ETK49_00605)	radA/sms	110440..111819 (+)	1380	WP_003178276.1	DNA repair protein RadA	Machinery gene
ETK49_RS00610 (ETK49_00610)	disA	111823..112899 (+)	1077	WP_003178277.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ETK49_RS00615 (ETK49_00615)	-	113031..114119 (+)	1089	WP_009330350.1	PIN/TRAM domain-containing protein	-
ETK49_RS00620 (ETK49_00620)	ispD	114136..114831 (+)	696	WP_009330349.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ETK49_RS00625 (ETK49_00625)	ispF	114824..115300 (+)	477	WP_003178280.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
ETK49_RS00630 (ETK49_00630)	gltX	115382..116839 (+)	1458	WP_009330348.1	glutamate--tRNA ligase	-
ETK49_RS00635 (ETK49_00635)	cysE	117141..117791 (+)	651	WP_003178282.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 40582.27 Da
• Isoelectric Point: 6.5986

>NTDB_id=300015 ETK49_RS00610 WP_003178277.1 111823..112899(+) (disA) [Bacillus licheniformis strain SRCM103608]
MDKDKKGAKQDLSEILQFVAPGTPLREGIENVLRAKTGGLIVVGFNDKVKEVVDGGFHINSSFSPAHLYELAKMDGAIIL
SDSGQKILYANTQLMPEATIPSSETGMRHRTAERVAKQTGCLIIAISERRNVITLYQENMKYILKDIGFILTKANQAIQT
LEKYKLILDHAISNLNALEFEELVTFGDVISVLHRYEMVLRIKNEINMYIKELGTEGHLIRLQVSELITDMEQEAALFVK
DYVKEKIKDPFVLLKQLQDMSSFELLDDAILLKLLGYSATTNMEEYVFPRGYRLLHKIPRLPMPIVENVVEAFGHLKLII
EADVKDLDEVEGIGAVRAQKIKKGLKRLQEKHYTDRQL

Nucleotide

• Length: 1077 bp

>NTDB_id=300015 ETK49_RS00610 WP_003178277.1 111823..112899(+) (disA) [Bacillus licheniformis strain SRCM103608]
ATGGACAAAGACAAAAAAGGAGCGAAACAGGATCTTTCAGAAATATTGCAGTTTGTCGCCCCCGGCACGCCTCTTCGCGA
AGGAATCGAAAACGTCCTTCGGGCCAAAACAGGCGGATTAATCGTGGTCGGCTTCAACGATAAAGTGAAAGAAGTGGTTG
ACGGAGGGTTCCACATAAATTCTTCTTTCTCTCCGGCTCATCTGTACGAGCTGGCTAAAATGGACGGGGCGATCATTCTC
AGCGATTCAGGGCAAAAAATTCTATATGCCAATACACAGCTCATGCCTGAGGCGACGATTCCCTCCTCTGAGACGGGCAT
GAGACACAGAACAGCCGAGCGTGTGGCCAAGCAGACCGGCTGTCTGATCATCGCGATTTCTGAAAGACGGAATGTGATTA
CGCTCTATCAGGAAAATATGAAATATATACTCAAAGATATCGGCTTTATCTTAACAAAAGCCAATCAGGCGATTCAGACG
CTCGAAAAATACAAACTCATTTTGGACCATGCGATTTCCAATTTGAACGCGCTGGAATTTGAAGAGCTTGTTACATTTGG
GGATGTCATCTCCGTTCTGCATCGATATGAAATGGTGCTCAGAATCAAAAACGAAATTAATATGTATATTAAAGAGCTTG
GAACAGAAGGCCATCTCATCAGACTCCAGGTTAGCGAACTGATCACCGATATGGAGCAGGAAGCGGCGCTGTTCGTCAAA
GATTATGTGAAAGAAAAAATCAAAGACCCGTTTGTTCTGCTGAAACAGCTTCAGGATATGTCGAGTTTCGAATTGCTGGA
TGATGCGATTCTCCTTAAGCTTTTAGGCTATTCAGCAACTACGAACATGGAAGAATACGTTTTTCCGAGAGGCTACAGGC
TTCTCCACAAAATTCCCCGCCTCCCGATGCCGATCGTCGAAAATGTTGTCGAAGCATTCGGCCATTTAAAGCTCATTATC
GAAGCGGATGTAAAAGATTTGGATGAAGTGGAAGGAATTGGGGCTGTTCGTGCCCAAAAGATAAAGAAAGGGTTAAAGAG
ACTTCAGGAGAAACATTATACTGACAGGCAGCTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (27-139)

• DisA bacterial checkpoint controller linker region (DisA-linker) (144-282)

3D structure

• AlphaFold DB: Q65PD4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	86.111	100	0.866