Detailed information NTG0029994

Bioinformatically predicted

Overview

• Name: amiA3
• Type: Regulator
• Locus tag: SPH_RS02305
• Genome accession: NC_010380
• Coordinates: 422552..424534 (+)
• Length: 660 a.a.
• NCBI ID: WP_000842600.1
• Uniprot ID: B1I9G7
• Organism: Streptococcus pneumoniae Hungary19A-6
• Function: binding to XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	421237..422190	422552..424534	flank	362

Gene organization within MGE regions

Location: 421237..424534

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPH_RS02300 (SPH_0473)	-	421237..422190 (-)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
SPH_RS02305 (SPH_0474)	amiA3	422552..424534 (+)	1983	WP_000842600.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 660 a.a.
• Molecular weight: 72954.59 Da
• Isoelectric Point: 4.7548

>NTDB_id=29994 SPH_RS02305 WP_000842600.1 422552..424534(+) (amiA3) [Streptococcus pneumoniae Hungary19A-6]
MKSSKLLALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPS
MAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWD
KDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSIKDNIVYTQQDSITYLVGTNIDRQSYKYTSK
TSDEQKASTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDV
NLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVIIDIQQLQKDEV
NNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEAT
DVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKW
MKEKEESNKKAQEDLAKHVK

Nucleotide

• Length: 1983 bp

>NTDB_id=29994 SPH_RS02305 WP_000842600.1 422552..424534(+) (amiA3) [Streptococcus pneumoniae Hungary19A-6]
ATGAAAAGTTCAAAACTACTTGCCCTTGCGGGCGTGACATTATTGGCGGCGACTACTTTAGCTGCATGCTCTGGATCAGG
TTCAAGCGCTAAAGGTGAGAAGACATTCTCATACATTTATGAGACAGACCCTGATAACCTCAACTATTTGACAACTGCTA
AGGCTGCGACAGCAAATATTACCAGTAACGTGGTTGATGGTTTGCTAGAAAATGATCGCTACGGGAACTTTGTGCCGTCT
ATGGCTGAGGATTGGTCTGTATCCAAGGATGGATTGACTTACACTTATACTATCCGTAAGGATGCAAAATGGTATACTTC
TGAAGGTGAAGAATACGCGGCAGTCAAAGCTCAAGACTTTGTAACAGGACTAAAATATGCTGCTGATAAAAAATCAGATG
CTCTTTACCTTGTTCAAGAATCAATCAAAGGGTTGGATGCCTATGTAAAAGGGGAAATCAAAGATTTCTCACAAGTAGGA
ATTAAGGCTCTGGATGAACAGACAGTTCAGTACACTTTGAACAAACCAGAAAGCTTCTGGAATTCTAAGACAACCATGGG
TGTGCTTGCGCCAGTTAATGAAGAGTTTTTGAATTCAAAAGGAGATGATTTTGCCAAAGCTACGGATCCAAGTAGTCTCT
TGTATAACGGTCCTTATTTGTTGAAATCCATTGTGACCAAATCTTCTGTTGAATTTGCGAAAAATCCGAACTACTGGGAT
AAGGACAATGTGCATATTGACAAAGTTAAATTGTCATTCTGGGATGGTCAAGATACCAGCAAACCTGCAGAAAACTTTAA
AGATGGTAGCCTTACAGCAGCTCGTCTCTATCCAACAAGTGCAAGTTTCGCAGAGCTTGAGAAGAGTATTAAGGACAATA
TTGTCTATACTCAACAAGACTCTATTACGTATCTAGTTGGTACAAATATTGACCGTCAGTCCTATAAATACACATCTAAG
ACCAGCGACGAACAAAAGGCATCGACTAAAAAGGCTCTCTTAAACAAGGATTTCCGTCAGGCTATTGCCTTTGGTTTTGA
TCGTACAGCCTATGCCTCTCAGTTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATATCTTTGTTCCACCAACAT
TTGTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTCACTTATGGGGATGAATGGAAGGATGTT
AATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAAGCCAAGGCTGAATTTGCTAAAGCTAAATCAGCCTTACA
AGCAGAAGGTGTGACTTTCCCAATTCATTTGGATATGCCAGTTGACCAGACAGCAACTACAAAAGTTCAGCGCGTCCAAT
CTATGAAACAATCCTTGGAAGCAACTTTAGGAGCTGATAATGTCATTATTGATATCCAACAACTACAAAAAGACGAAGTA
AACAATATTACATATTTTGCTGAAAATGCTGCTGGCGAAGACTGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTT
TGCCGATCCATCAACCTACCTTGATATTATCAAACCTTCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAG
GGGAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAGGCTGGTGATGAGGCTACA
GATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCTTGGTTGACAGATAGTGCTTTGATTATTCCAACTACATC
TCGTACAGGGCGTCCAATCTTGTCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGTACAAGTG
AACCAGTCTTGTATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAAAAAGCTCAGGAAAAATGG
ATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGATCTCGCAAAACATGTGAAATAA

Domains

Predicted by InterproScan.

• Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5) (77-519)

3D structure

• AlphaFold DB: B1I9G7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiA3	Streptococcus thermophilus LMD-9	58.245	100	0.583
amiA3	Streptococcus thermophilus LMG 18311	57.943	100	0.58
amiA	Streptococcus salivarius strain HSISS4	57.943	100	0.58