Detailed information NTG0299811

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: DP204_RS18220
• Genome accession: NZ_CP030171
• Coordinates: 3620192..3620788 (-)
• Length: 198 a.a.
• NCBI ID: WP_023289053.1
• Uniprot ID: A0A2N4W2M8
• Organism: Klebsiella quasipneumoniae subsp. quasipneumoniae strain A708
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	3609195..3623069	3620192..3620788	within	0

Gene organization within MGE regions

Location: 3609195..3623069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP204_RS18180 (DP204_18185)	tnpB	3609195..3609545 (+)	351	WP_032414478.1	IS66 family insertion sequence element accessory protein TnpB	-
DP204_RS18185 (DP204_18190)	tnpC	3609575..3611164 (+)	1590	WP_060415438.1	IS66 family transposase	-
DP204_RS18190 (DP204_18195)	-	3611171..3613384 (-)	2214	WP_410321445.1	hypothetical protein	-
DP204_RS28695	-	3613397..3613750 (-)	354	Protein_3525	BapA/Bap/LapF family prefix-like domain-containing protein	-
DP204_RS18195 (DP204_18200)	-	3614365..3614778 (-)	414	WP_112201718.1	CoA-binding protein	-
DP204_RS18200 (DP204_18205)	mgsA	3614933..3615391 (+)	459	WP_004201439.1	methylglyoxal synthase	-
DP204_RS18205 (DP204_18210)	helD	3615403..3617457 (-)	2055	WP_112201719.1	DNA helicase IV	-
DP204_RS18210 (DP204_18215)	-	3617582..3618028 (+)	447	WP_004201437.1	YccF domain-containing protein	-
DP204_RS18215 (DP204_18220)	yccS	3618046..3620181 (+)	2136	WP_023289054.1	YccS family putative transporter	-
DP204_RS18220 (DP204_18225)	sxy/tfoX	3620192..3620788 (-)	597	WP_023289053.1	TfoX/Sxy family DNA transformation protein	Regulator
DP204_RS28145	-	3620806..3621111 (-)	306	WP_181573406.1	hypothetical protein	-
DP204_RS18230 (DP204_18235)	sulA	3621137..3621646 (+)	510	WP_023289052.1	SOS-induced cell division inhibitor SulA	-
DP204_RS18235 (DP204_18240)	ompA	3621999..3623069 (+)	1071	WP_044521956.1	porin OmpA	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 22670.34 Da
• Isoelectric Point: 10.2333

>NTDB_id=299811 DP204_RS18220 WP_023289053.1 3620192..3620788(-) (sxy/tfoX) [Klebsiella quasipneumoniae subsp. quasipneumoniae strain A708]
MRKLVCPRLPQFQACVSPLGQLHSRPLFGGYSLAIEDTVFAMVAEGNIYLKACEQSAAYRVEHHNPLLMLRRHGRIVPLK
YYQIDDALWRDEKQLFRLSLMSWQSAQREKYRRRSSGRLKDLPNISFHMELQLIHSGIPDVLALREVGARQAWLKLRENN
ASLSHNVLLALEGAIVGVHAAALPTPRRQELLEWASAR

Nucleotide

• Length: 597 bp

>NTDB_id=299811 DP204_RS18220 WP_023289053.1 3620192..3620788(-) (sxy/tfoX) [Klebsiella quasipneumoniae subsp. quasipneumoniae strain A708]
ATGAGAAAACTCGTATGTCCGCGGCTCCCGCAATTTCAGGCCTGCGTCTCTCCGCTGGGTCAACTTCACTCTCGCCCCCT
GTTTGGCGGCTACAGCTTGGCTATCGAAGATACCGTGTTTGCGATGGTGGCAGAGGGGAATATTTATCTAAAGGCCTGCG
AGCAGAGCGCTGCCTATCGGGTAGAACACCATAATCCTTTATTGATGCTGCGCCGACACGGGCGCATCGTGCCGCTAAAG
TATTATCAAATCGACGATGCCTTGTGGCGCGATGAGAAACAGCTTTTCCGCTTGTCGCTGATGTCGTGGCAGAGCGCCCA
GCGTGAAAAATATCGCCGCCGGTCGTCGGGACGCCTGAAGGATTTACCCAATATCAGCTTTCATATGGAATTGCAGCTGA
TTCACTCGGGCATTCCAGACGTGTTAGCACTACGGGAGGTGGGCGCCCGCCAGGCCTGGCTAAAGCTGCGCGAGAACAAT
GCTTCCCTATCGCACAACGTCTTGCTGGCGCTGGAGGGGGCTATCGTTGGCGTTCATGCCGCCGCGCTCCCGACGCCACG
GCGTCAGGAGCTTCTGGAATGGGCGTCTGCGCGCTAA

Domains

Predicted by InterproScan.

• TfoX N-terminal domain (TfoX_N) (16-105)

• TfoX C-terminal domain (TfoX_C) (117-194)

3D structure

• AlphaFold DB: A0A2N4W2M8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Escherichia coli BW25113 strain K-12	49.746	99.495	0.495