Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SP70585_RS01160 Genome accession   NC_012468
Coordinates   207986..208426 (-) Length   146 a.a.
NCBI ID   WP_000861967.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 70585     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 202986..213426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS01135 (SP70585_0230) - 203247..204533 (+) 1287 WP_000278877.1 response regulator transcription factor -
  SP70585_RS01140 (SP70585_0231) - 204585..205118 (+) 534 WP_000729029.1 hypothetical protein -
  SP70585_RS01145 (SP70585_0232) nrdI 205196..205666 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  SP70585_RS01150 (SP70585_0233) - 205959..207221 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  SP70585_RS01155 (SP70585_0234) - 207531..207989 (-) 459 WP_000745055.1 DUF3021 domain-containing protein -
  SP70585_RS01160 (SP70585_0235) brsR 207986..208426 (-) 441 WP_000861967.1 LytTR family DNA-binding domain-containing protein Regulator
  SP70585_RS14110 - 208514..208639 (-) 126 WP_001822433.1 hypothetical protein -
  SP70585_RS13505 (SP70585_0237) - 208747..208893 (+) 147 Protein_232 DNA mismatch repair protein -
  SP70585_RS01170 (SP70585_0238) ribE 209218..209685 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  SP70585_RS01175 (SP70585_0239) - 209686..210891 (-) 1206 WP_001818099.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  SP70585_RS01180 (SP70585_0240) ribE 210911..211546 (-) 636 WP_000493838.1 riboflavin synthase -
  SP70585_RS01185 (SP70585_0241) ribD 211531..212631 (-) 1101 WP_001284099.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17151.84 Da        Isoelectric Point: 5.9797

>NTDB_id=29977 SP70585_RS01160 WP_000861967.1 207986..208426(-) (brsR) [Streptococcus pneumoniae 70585]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLIEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=29977 SP70585_RS01160 WP_000861967.1 207986..208426(-) (brsR) [Streptococcus pneumoniae 70585]
ATGAAAGTAGAATTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
TCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGATAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.735

100

0.37

Multiple sequence alignment