Detailed information NTG0299743

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: BVDSYZ_RS18645
• Genome accession: NZ_CP030150
• Coordinates: 3723202..3724365 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain DSYZ
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3718202..3729365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BVDSYZ_RS18615 (BVDSYZ_18615)	-	3718467..3718886 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
BVDSYZ_RS18620 (BVDSYZ_18620)	comFC	3718960..3719649 (-)	690	WP_199776864.1	phosphoribosyltransferase family protein	Machinery gene
BVDSYZ_RS18625 (BVDSYZ_18625)	-	3719655..3719939 (-)	285	WP_003151389.1	competence protein ComFB	-
BVDSYZ_RS18630 (BVDSYZ_18630)	comFA	3719997..3721382 (-)	1386	WP_040238815.1	DEAD/DEAH box helicase	Machinery gene
BVDSYZ_RS18635 (BVDSYZ_18635)	-	3721490..3722338 (-)	849	WP_015418336.1	DegV family protein	-
BVDSYZ_RS18640 (BVDSYZ_18640)	degU	3722436..3723125 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
BVDSYZ_RS18645 (BVDSYZ_18645)	degS	3723202..3724365 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
BVDSYZ_RS18650 (BVDSYZ_18650)	-	3724588..3725235 (+)	648	WP_003151384.1	YigZ family protein	-
BVDSYZ_RS18655 (BVDSYZ_18655)	-	3725240..3726454 (+)	1215	WP_015418337.1	LCP family protein	-
BVDSYZ_RS18660 (BVDSYZ_18660)	-	3726544..3727620 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
BVDSYZ_RS18665 (BVDSYZ_18665)	-	3727753..3728949 (-)	1197	WP_039253634.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=299743 BVDSYZ_RS18645 WP_007407484.1 3723202..3724365(-) (degS) [Bacillus velezensis strain DSYZ]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=299743 BVDSYZ_RS18645 WP_007407484.1 3723202..3724365(-) (degS) [Bacillus velezensis strain DSYZ]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951