Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BVDSYZ_RS05935 Genome accession   NZ_CP030150
Coordinates   1168735..1169391 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain DSYZ     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1163735..1174391
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BVDSYZ_RS05910 (BVDSYZ_05910) oppF 1164265..1165182 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  BVDSYZ_RS05915 (BVDSYZ_05915) - 1165289..1166476 (+) 1188 WP_062623314.1 putative glycoside hydrolase -
  BVDSYZ_RS05920 (BVDSYZ_05920) - 1166594..1167172 (+) 579 WP_061890537.1 GNAT family N-acetyltransferase -
  BVDSYZ_RS05925 (BVDSYZ_05925) spx 1167350..1167745 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  BVDSYZ_RS05930 (BVDSYZ_05930) - 1167803..1168459 (-) 657 WP_007409109.1 TerC family protein -
  BVDSYZ_RS05935 (BVDSYZ_05935) mecA 1168735..1169391 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  BVDSYZ_RS05940 (BVDSYZ_05940) - 1169542..1170729 (+) 1188 WP_015417214.1 competence protein CoiA family protein -
  BVDSYZ_RS05945 (BVDSYZ_05945) pepF 1170932..1172761 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  BVDSYZ_RS22045 - 1172799..1172966 (-) 168 WP_003155026.1 hypothetical protein -
  BVDSYZ_RS05950 (BVDSYZ_05950) spxH 1173252..1174154 (-) 903 WP_039251990.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=299700 BVDSYZ_RS05935 WP_003155032.1 1168735..1169391(+) (mecA) [Bacillus velezensis strain DSYZ]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=299700 BVDSYZ_RS05935 WP_003155032.1 1168735..1169391(+) (mecA) [Bacillus velezensis strain DSYZ]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment