Detailed information NTG0299576

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ES969_RS00595
• Genome accession: NZ_CP035402
• Coordinates: 108454..109536 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain SRCM103576
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 103454..114536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES969_RS00580 (ES969_00580)	mcsB	103462..104553 (+)	1092	WP_003235007.1	protein arginine kinase	-
ES969_RS00585 (ES969_00585)	clpC	104550..106982 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
ES969_RS00590 (ES969_00590)	radA/sms	107074..108450 (+)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
ES969_RS00595 (ES969_00595)	disA	108454..109536 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ES969_RS00600 (ES969_00600)	yacL	109652..110752 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
ES969_RS00605 (ES969_00605)	ispD	110767..111465 (+)	699	WP_014478616.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ES969_RS00610 (ES969_00610)	ispF	111458..111934 (+)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
ES969_RS00615 (ES969_00615)	gltX	112025..113476 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
ES969_RS00625 (ES969_00625)	cysE	113778..114431 (+)	654	WP_014478618.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=299576 ES969_RS00595 WP_003225736.1 108454..109536(+) (disA) [Bacillus subtilis strain SRCM103576]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=299576 ES969_RS00595 WP_003225736.1 108454..109536(+) (disA) [Bacillus subtilis strain SRCM103576]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTCCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1