Detailed information NTG0299455

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DP111_RS11145
• Genome accession: NZ_CP030124
• Coordinates: 2212569..2213765 (+)
• Length: 398 a.a.
• NCBI ID: WP_043032834.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SH1510
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2207569..2218765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP111_RS11115 (DP111_11115)	-	2208228..2210807 (+)	2580	WP_012028056.1	YfhO family protein	-
DP111_RS11135 (DP111_11135)	-	2211208..2211891 (-)	684	WP_012775416.1	YoaK family protein	-
DP111_RS11140 (DP111_11140)	rlmH	2211916..2212395 (-)	480	WP_023371894.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DP111_RS11145 (DP111_11145)	htrA	2212569..2213765 (+)	1197	WP_043032834.1	trypsin-like peptidase domain-containing protein	Regulator
DP111_RS11150 (DP111_11150)	spo0J	2213826..2214590 (+)	765	WP_014638879.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41804.81 Da
• Isoelectric Point: 4.6655

>NTDB_id=299455 DP111_RS11145 WP_043032834.1 2212569..2213765(+) (htrA) [Streptococcus suis strain SH1510]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPRVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTVSTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=299455 DP111_RS11145 WP_043032834.1 2212569..2213765(+) (htrA) [Streptococcus suis strain SH1510]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAGCCACGGGTTCAACAAGCAAATTCTGCCATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCTACTACAAAGGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCTGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAGTCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (293-389)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.194	99.749	0.59
htrA	Streptococcus gordonii str. Challis substr. CH1	59.241	99.246	0.588
htrA	Streptococcus pneumoniae D39	56.997	98.744	0.563
htrA	Streptococcus pneumoniae TIGR4	56.997	98.744	0.563
htrA	Streptococcus mitis NCTC 12261	56.997	98.744	0.563
htrA	Streptococcus pneumoniae R6	56.997	98.744	0.563
htrA	Streptococcus pneumoniae Rx1	56.997	98.744	0.563