Detailed information NTG0299444

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DP111_RS08835
• Genome accession: NZ_CP030124
• Coordinates: 1740313..1742550 (-)
• Length: 745 a.a.
• NCBI ID: WP_043033064.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SH1510
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1735313..1747550

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP111_RS08810 (DP111_08810)	tmk	1735419..1736057 (-)	639	WP_002935358.1	dTMP kinase	-
DP111_RS08815 (DP111_08815)	-	1736232..1737098 (+)	867	WP_002935357.1	YitT family protein	-
DP111_RS08820 (DP111_08820)	-	1737135..1738406 (-)	1272	WP_002935355.1	toxic anion resistance protein	-
DP111_RS08825 (DP111_08825)	-	1738412..1739239 (-)	828	WP_002935354.1	hypothetical protein	-
DP111_RS08830 (DP111_08830)	-	1739333..1739989 (-)	657	WP_002935353.1	CBS domain-containing protein	-
DP111_RS11215	-	1740171..1740296 (-)	126	Protein_1668	IS982 family transposase	-
DP111_RS08835 (DP111_08835)	comEC/celB	1740313..1742550 (-)	2238	WP_043033064.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DP111_RS08840 (DP111_08840)	comEA/celA/cilE	1742534..1743196 (-)	663	WP_079394055.1	helix-hairpin-helix domain-containing protein	Machinery gene
DP111_RS08845 (DP111_08845)	-	1743267..1744013 (-)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
DP111_RS08850 (DP111_08850)	-	1744159..1745604 (+)	1446	WP_114876557.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
DP111_RS08855 (DP111_08855)	-	1745756..1746556 (+)	801	WP_013730319.1	ABC transporter ATP-binding protein	-
DP111_RS08860 (DP111_08860)	-	1746553..1747482 (+)	930	WP_009909659.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84157.32 Da
• Isoelectric Point: 8.1369

>NTDB_id=299444 DP111_RS08835 WP_043033064.1 1740313..1742550(-) (comEC/celB) [Streptococcus suis strain SH1510]
MLRSIKLPCQPIHLALLAVAAYFVVRSFSLLTMGLLSLVLAVFGVRQGKAVFLRTLPLLALCGLFFGFQKLQWNRADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQELADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITVIKKIVPVQSRNVFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCFLLL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMIYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPIIKITWVNGFFVLMEKIIVWVADLGLRPWILGKPSVVILILLLVCLFLLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFMRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVHIGRIYVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=299444 DP111_RS08835 WP_043033064.1 1740313..1742550(-) (comEC/celB) [Streptococcus suis strain SH1510]
ATGTTACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCGCTC
TTTTTCCCTCTTGACAATGGGCCTGCTCAGTTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGGCAGTTTTCCTCA
GAACGCTGCCGCTTCTAGCCCTGTGTGGTCTCTTTTTCGGATTTCAAAAGCTTCAATGGAATCGAGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCCTTTCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGAGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTACGGTAATCAAGAAGATTGTCCCTGTCCAGTCTAGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACAGTTTTTGTCTGTTTCTTGTTGCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTGATGATCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACTTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTCTTGATGGAAAAAATTATTGTCTGGGT
GGCAGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGTGGTAATTCTTATTCTCTTGCTGGTCTGTCTCTTCT
TACTTTATGATTTCCACAGAAAAAAGAAATGGCTCTTAGGACTGAGCCTGGTCCTTGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGTGACAGCATCTTTATGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTTCTGACACACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTCCATATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATTAATGTGCCTGTCCATGTGGTCAAAGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-172)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.24	99.732	0.541
comEC/celB	Streptococcus mitis NCTC 12261	53.414	100	0.536
comEC/celB	Streptococcus pneumoniae TIGR4	52.463	100	0.529
comEC/celB	Streptococcus pneumoniae Rx1	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae D39	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae R6	52.197	100	0.526
comEC	Lactococcus lactis subsp. cremoris KW2	49.332	100	0.495