Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ES965_RS20585 Genome accession   NZ_CP035391
Coordinates   3962965..3963654 (-) Length   229 a.a.
NCBI ID   WP_003243527.1    Uniprot ID   P42421
Organism   Bacillus subtilis strain SRCM103689     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3957965..3968654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES965_RS20565 (ES965_20565) yxeA 3958870..3959217 (-) 348 WP_024572303.1 YxeA family protein -
  ES965_RS20570 (ES965_20570) yxdM 3959231..3961099 (-) 1869 WP_129092820.1 ABC transporter permease YxdM -
  ES965_RS20575 (ES965_20575) yxdL 3961074..3961847 (-) 774 WP_024572301.1 ABC transporter ATP-binding protein YxdL -
  ES965_RS20580 (ES965_20580) yxdK 3961991..3962968 (-) 978 WP_129092821.1 two-component system sensor histidine kinase YxdK -
  ES965_RS20585 (ES965_20585) braR 3962965..3963654 (-) 690 WP_003243527.1 two-component system response regulator YxdJ Regulator
  ES965_RS20590 (ES965_20590) iolJ 3963762..3964634 (-) 873 WP_129092822.1 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase -
  ES965_RS20595 (ES965_20595) iolI 3964655..3965491 (-) 837 WP_015250853.1 2-keto-myo-inositol isomerase -
  ES965_RS20600 (ES965_20600) iolH 3965577..3966446 (-) 870 WP_086344514.1 sugar phosphate isomerase/epimerase -
  ES965_RS20605 (ES965_20605) iolG 3966466..3967500 (-) 1035 WP_014481414.1 bifunctional inositol 2-dehydrogenase/D-chiro-inositol 1-dehydrogenase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26600.34 Da        Isoelectric Point: 4.8564

>NTDB_id=298804 ES965_RS20585 WP_003243527.1 3962965..3963654(-) (braR) [Bacillus subtilis strain SRCM103689]
MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREKPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISA
RSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKES
KLLEVLLERGEKVTSRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRELNAPVSIEAVRGEGYQLRAQS

Nucleotide


Download         Length: 690 bp        

>NTDB_id=298804 ES965_RS20585 WP_003243527.1 3962965..3963654(-) (braR) [Bacillus subtilis strain SRCM103689]
TTGAATAAAATTATGATTGTGGAAGACAGTGAAGACATTCGCGGACTATTGCAGAATTACCTTGAAAAATACGGATATCA
AACAGTGGTCGCCGCGGATTTTACAGCTGTTCTTGATGTCTTTTTGCGGGAAAAGCCCGATGTGGTGCTGCTTGATATCA
ATTTGCCGGCATATGACGGATATTATTGGTGCCGGCAGATCCGCCAGCACTCCACAAGCCCGATCATCTTTATTTCTGCC
AGAAGCGGGGAAATGGATCAGGTGATGGCGATTGAAAACGGGGGAGACGATTATATCGAAAAACCGTTTTCTTATGATAT
TGTGCTGGCGAAAATCAAAAGCCAGATCCGGAGGGCGTACGGGGAGTACGCCGCAAAGCAGGGAGAGAAAGTGGTTGAAT
ATGCCGGCGTCCAGCTCTTTGTGGAACGGTTTGAACTGCGTTTTCAGGATGAAAAAAGCGAGCTTTCTAAAAAAGAAAGC
AAGCTTTTGGAAGTGCTGCTTGAGCGGGGAGAAAAGGTGACGAGTCGGGACCGTCTCATGGAAAAGACGTGGGACACCGA
CATATTCATCGATGATAATACACTTAACGTGTATATCACGCGGCTCAGAAAAAAACTGCGGGAGCTGAATGCGCCTGTTT
CTATTGAAGCGGTGCGGGGCGAAGGCTACCAGCTGAGGGCGCAGTCATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P42421

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

41.704

97.38

0.406