Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ES963_RS21345 Genome accession   NZ_CP035390
Coordinates   3979536..3980225 (-) Length   229 a.a.
NCBI ID   WP_003243527.1    Uniprot ID   P42421
Organism   Bacillus subtilis strain SRCM103641     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3974536..3985225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES963_RS21325 (ES963_21325) yxeA 3975441..3975788 (-) 348 WP_003227084.1 YxeA family protein -
  ES963_RS21330 (ES963_21330) yxdM 3975802..3977670 (-) 1869 WP_087614826.1 ABC transporter permease YxdM -
  ES963_RS21335 (ES963_21335) yxdL 3977645..3978418 (-) 774 WP_003243557.1 ABC transporter ATP-binding protein YxdL -
  ES963_RS21340 (ES963_21340) yxdK 3978562..3979539 (-) 978 WP_015250855.1 two-component system sensor histidine kinase YxdK -
  ES963_RS21345 (ES963_21345) braR 3979536..3980225 (-) 690 WP_003243527.1 two-component system response regulator YxdJ Regulator
  ES963_RS21350 (ES963_21350) iolJ 3980334..3981206 (-) 873 WP_015250854.1 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase -
  ES963_RS21355 (ES963_21355) iolI 3981227..3982063 (-) 837 WP_015250853.1 2-keto-myo-inositol isomerase -
  ES963_RS21360 (ES963_21360) iolH 3982149..3983018 (-) 870 WP_015250852.1 sugar phosphate isomerase/epimerase -
  ES963_RS21365 (ES963_21365) iolG 3983038..3984072 (-) 1035 WP_015250851.1 bifunctional inositol 2-dehydrogenase/D-chiro-inositol 1-dehydrogenase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26600.34 Da        Isoelectric Point: 4.8564

>NTDB_id=298652 ES963_RS21345 WP_003243527.1 3979536..3980225(-) (braR) [Bacillus subtilis strain SRCM103641]
MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREKPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISA
RSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKES
KLLEVLLERGEKVTSRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRELNAPVSIEAVRGEGYQLRAQS

Nucleotide


Download         Length: 690 bp        

>NTDB_id=298652 ES963_RS21345 WP_003243527.1 3979536..3980225(-) (braR) [Bacillus subtilis strain SRCM103641]
TTGAATAAAATTATGATTGTGGAAGACAGTGAAGACATTCGCGGACTATTGCAGAATTACCTTGAAAAATACGGATATCA
AACAGTGGTCGCCGCGGATTTTACAGCTGTTCTTGATGTCTTTTTGCGGGAAAAGCCCGATGTGGTGCTGCTTGATATCA
ATTTGCCGGCATATGACGGATATTATTGGTGCCGGCAGATCCGCCAGCACTCCACAAGCCCGATCATCTTTATTTCTGCC
AGAAGCGGAGAAATGGATCAGGTGATGGCGATTGAAAACGGGGGAGACGATTATATCGAAAAACCGTTTTCTTATGATAT
TGTGCTGGCGAAAATCAAAAGCCAGATCCGGAGGGCGTACGGGGAGTACGCCGCAAAGCAGGGAGAGAAAGTGGTTGAAT
ATGCCGGCGTTCAACTCTTTGTGGAACGGTTTGAACTGCGTTTTCAGGATGAAAAAAGCGAGCTTTCTAAAAAAGAAAGC
AAGCTTTTGGAAGTGCTGCTTGAGCGGGGAGAAAAGGTGACGAGTCGGGACCGTCTCATGGAAAAGACGTGGGACACCGA
CATATTCATCGATGATAATACACTTAACGTGTATATCACGCGGCTCAGAAAAAAACTGCGGGAGCTGAATGCGCCTGTTT
CTATTGAAGCGGTGCGGGGCGAAGGCTACCAGCTGAGGGCGCAGTCATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P42421

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

41.704

97.38

0.406