Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ES963_RS03030 Genome accession   NZ_CP035390
Coordinates   573176..573817 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain SRCM103641     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 568176..578817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES963_RS03000 (ES963_03000) ydfE 569371..569994 (-) 624 WP_014478968.1 flavin reductase family protein -
  ES963_RS03005 (ES963_03005) ydfF 570084..570764 (+) 681 WP_014478969.1 winged helix-turn-helix domain-containing protein -
  ES963_RS03010 (ES963_03010) ydfG 570844..571287 (-) 444 WP_015252723.1 carboxymuconolactone decarboxylase family protein -
  ES963_RS03015 (ES963_03015) - 571373..571552 (-) 180 WP_080019537.1 hypothetical protein -
  ES963_RS03020 (ES963_03020) - 571549..571692 (-) 144 WP_014478971.1 hypothetical protein -
  ES963_RS03025 (ES963_03025) ydfH 571960..573183 (+) 1224 WP_015252722.1 two-component system sensor histidine kinase YdfH -
  ES963_RS03030 (ES963_03030) vraR 573176..573817 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  ES963_RS03035 (ES963_03035) pleJ 573933..576107 (+) 2175 WP_046160096.1 MMPL family transporter -
  ES963_RS03040 (ES963_03040) ydfK 576165..576854 (-) 690 WP_046160097.1 DUF554 domain-containing protein -
  ES963_RS03045 (ES963_03045) ydfL 576943..577755 (-) 813 WP_087614363.1 MerR family transcriptional regulator -
  ES963_RS03050 (ES963_03050) mneP 577869..578762 (-) 894 WP_038428417.1 manganese transporter MneP -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=298531 ES963_RS03030 WP_003244318.1 573176..573817(+) (vraR) [Bacillus subtilis strain SRCM103641]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=298531 ES963_RS03030 WP_003244318.1 573176..573817(+) (vraR) [Bacillus subtilis strain SRCM103641]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTGTTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362

Multiple sequence alignment