Detailed information NTG0298495

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DK877_RS08315
• Genome accession: NZ_CP030023
• Coordinates: 1673328..1674377 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis strain ISU2414
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1668328..1679377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK877_RS08295 (DK877_08550)	nadE	1669156..1669980 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
DK877_RS08300 (DK877_08555)	-	1670854..1671381 (-)	528	WP_004194600.1	VanZ family protein	-
DK877_RS08305 (DK877_08560)	rlmN	1671378..1672490 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DK877_RS08310 (DK877_08565)	-	1672499..1673140 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
DK877_RS08315 (DK877_08570)	sepM	1673328..1674377 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
DK877_RS08320 (DK877_08575)	coaD	1674364..1674852 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
DK877_RS08325 (DK877_08580)	rsmD	1674842..1675381 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DK877_RS08330 (DK877_08585)	-	1675680..1676402 (-)	723	WP_013730502.1	hypothetical protein	-
DK877_RS08335 (DK877_08590)	-	1676459..1676845 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
DK877_RS08340 (DK877_08595)	-	1676845..1677063 (-)	219	WP_004194736.1	YqgQ family protein	-
DK877_RS08345 (DK877_08600)	-	1677363..1677965 (-)	603	WP_004194738.1	response regulator transcription factor	-
DK877_RS08350 (DK877_08605)	-	1677962..1679056 (-)	1095	WP_024394990.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=298495 DK877_RS08315 WP_009910567.1 1673328..1674377(-) (sepM) [Streptococcus suis strain ISU2414]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=298495 DK877_RS08315 WP_009910567.1 1673328..1674377(-) (sepM) [Streptococcus suis strain ISU2414]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602