Detailed information NTG0298478

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DK877_RS03500
• Genome accession: NZ_CP030023
• Coordinates: 671467..673695 (-)
• Length: 742 a.a.
• NCBI ID: WP_053863290.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2414
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 666467..678695

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK877_RS03485 (DK877_03575)	-	668678..669880 (-)	1203	WP_002935295.1	IS110-like element ISSsu7 family transposase	-
DK877_RS03490 (DK877_03580)	-	670457..670765 (-)	309	WP_002938710.1	DUF1827 family protein	-
DK877_RS03495 (DK877_03585)	-	670820..671281 (-)	462	WP_002938708.1	NUDIX hydrolase	-
DK877_RS03500 (DK877_03590)	clpE	671467..673695 (-)	2229	WP_053863290.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DK877_RS03505 (DK877_03595)	-	673919..674149 (+)	231	WP_002938704.1	DUF1797 family protein	-
DK877_RS03510 (DK877_03600)	-	674275..674964 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
DK877_RS03515 (DK877_03605)	-	674957..675691 (+)	735	WP_002938699.1	amino acid ABC transporter ATP-binding protein	-
DK877_RS03520 (DK877_03610)	-	675821..676669 (+)	849	WP_002938697.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
DK877_RS03525 (DK877_03620)	-	678107..678400 (+)	294	WP_002938694.1	hypothetical protein	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82698.02 Da
• Isoelectric Point: 5.2167

>NTDB_id=298478 DK877_RS03500 WP_053863290.1 671467..673695(-) (clpE) [Streptococcus suis strain ISU2414]
MLCKNCNINDATIHLYNNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGEHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDASLERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=298478 DK877_RS03500 WP_053863290.1 671467..673695(-) (clpE) [Streptococcus suis strain ISU2414]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACAACAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAACATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCTACTCAAGCCGGTGAGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCTCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTAACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGGAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAACAATTAGCTATCGAACTCTTCGGTTCGGCAGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACAGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGTCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACTATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTGCGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• AAA lid domain (AAA_lid_9) (291-389)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	81.963	100	0.833
clpE	Streptococcus pneumoniae D39	81.963	100	0.833
clpE	Streptococcus pneumoniae R6	81.963	100	0.833
clpE	Streptococcus pneumoniae TIGR4	81.963	100	0.833
clpE	Streptococcus mutans UA159	82.109	100	0.829
clpC	Lactococcus lactis subsp. cremoris KW2	77.241	97.709	0.755
clpC	Bacillus subtilis subsp. subtilis str. 168	52.308	87.601	0.458
clpC	Streptococcus thermophilus LMD-9	48.089	84.636	0.407
clpC	Streptococcus mutans UA159	48.397	84.097	0.407
clpC	Streptococcus thermophilus LMG 18311	47.771	84.636	0.404
clpC	Streptococcus pneumoniae D39	47.68	84.232	0.402
clpC	Streptococcus pneumoniae TIGR4	47.68	84.232	0.402
clpC	Streptococcus pneumoniae Rx1	47.68	84.232	0.402
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.656	84.636	0.395