Detailed information    

insolico Bioinformatically predicted

Overview


Name   treR   Type   Regulator
Locus tag   DK877_RS01230 Genome accession   NZ_CP030023
Coordinates   224437..225150 (+) Length   237 a.a.
NCBI ID   WP_012774930.1    Uniprot ID   A0A142UPI2
Organism   Streptococcus suis strain ISU2414     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 208211..254233 224437..225150 within 0


Gene organization within MGE regions


Location: 208211..254233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK877_RS01165 (DK877_01200) - 208211..209155 (+) 945 WP_024409330.1 IS30 family transposase -
  DK877_RS01170 (DK877_01205) - 209213..210241 (+) 1029 WP_002935967.1 ABC transporter substrate-binding protein -
  DK877_RS01175 (DK877_01210) - 210335..211144 (+) 810 WP_002935966.1 hypothetical protein -
  DK877_RS11275 - 211317..213378 (+) 2062 Protein_202 heavy metal translocating P-type ATPase -
  DK877_RS01195 (DK877_01230) - 213417..215906 (-) 2490 WP_053338565.1 ATP-dependent RecD-like DNA helicase -
  DK877_RS01200 (DK877_01235) lepB 215970..216599 (-) 630 WP_002935959.1 signal peptidase I -
  DK877_RS01205 (DK877_01240) rnhC 216609..217499 (-) 891 WP_013730101.1 ribonuclease HIII -
  DK877_RS01210 (DK877_01245) - 217584..218567 (+) 984 WP_009909178.1 Gfo/Idh/MocA family protein -
  DK877_RS01215 (DK877_01250) - 218916..220091 (+) 1176 WP_013730102.1 LysM domain-containing protein -
  DK877_RS01220 (DK877_01255) treC 220504..222129 (-) 1626 WP_009909185.1 alpha,alpha-phosphotrehalase -
  DK877_RS01225 (DK877_01260) treP 222210..224204 (-) 1995 WP_002935953.1 PTS system trehalose-specific EIIBC component -
  DK877_RS01230 (DK877_01265) treR 224437..225150 (+) 714 WP_012774930.1 trehalose operon repressor Regulator
  DK877_RS01235 (DK877_01270) - 225208..225519 (+) 312 WP_002935948.1 hypothetical protein -
  DK877_RS01240 (DK877_01275) - 225516..226064 (+) 549 WP_002935945.1 CvpA family protein -
  DK877_RS01245 (DK877_01285) - 226615..228948 (+) 2334 WP_053863258.1 endonuclease MutS2 -
  DK877_RS01250 (DK877_01290) - 229114..229506 (+) 393 WP_014636774.1 DUF1310 family protein -
  DK877_RS01255 (DK877_01295) - 229499..229762 (+) 264 WP_022540536.1 hypothetical protein -
  DK877_RS01260 (DK877_01300) - 229788..230165 (+) 378 WP_002935940.1 DUF1310 family protein -
  DK877_RS01265 (DK877_01305) - 230212..230469 (+) 258 WP_002935939.1 hypothetical protein -
  DK877_RS01270 (DK877_01310) - 230564..230953 (+) 390 WP_002935938.1 DUF1310 family protein -
  DK877_RS01275 (DK877_01315) - 230946..232196 (+) 1251 WP_002935930.1 Mbeg1-like protein -
  DK877_RS01280 (DK877_01320) - 232298..232675 (+) 378 WP_024390453.1 DUF1310 family protein -
  DK877_RS01285 (DK877_01325) - 232678..232980 (+) 303 WP_029694155.1 hypothetical protein -
  DK877_RS01290 (DK877_01330) - 233075..233455 (+) 381 WP_002935927.1 DUF1310 family protein -
  DK877_RS01295 (DK877_01335) - 233462..234724 (+) 1263 WP_002935926.1 triacylglycerol lipase -
  DK877_RS01300 (DK877_01340) - 234703..235089 (+) 387 WP_002935925.1 hypothetical protein -
  DK877_RS01305 (DK877_01345) - 235102..235422 (+) 321 WP_002935924.1 hypothetical protein -
  DK877_RS01310 (DK877_01350) trxA 235662..235976 (+) 315 WP_002935923.1 thioredoxin -
  DK877_RS11300 - 236069..236119 (-) 51 WP_353735889.1 hypothetical protein -
  DK877_RS01315 (DK877_01355) - 236109..237638 (+) 1530 WP_009909192.1 AMP-binding protein -
  DK877_RS01320 (DK877_01360) msrB 237678..238619 (+) 942 WP_009909193.1 peptide-methionine (R)-S-oxide reductase MsrB -
  DK877_RS01325 (DK877_01365) - 238811..239155 (+) 345 WP_014636777.1 hypothetical protein -
  DK877_RS01330 (DK877_01370) - 239152..239385 (+) 234 WP_002935912.1 hypothetical protein -
  DK877_RS01335 (DK877_01375) - 239463..239873 (+) 411 WP_002935911.1 hypothetical protein -
  DK877_RS01340 (DK877_01380) - 239873..240148 (+) 276 WP_002935908.1 hypothetical protein -
  DK877_RS01345 (DK877_01385) - 240174..240575 (+) 402 WP_014636783.1 hypothetical protein -
  DK877_RS01350 (DK877_01390) - 240572..241786 (+) 1215 WP_002935904.1 alpha/beta fold hydrolase -
  DK877_RS01355 (DK877_01395) - 241771..242160 (+) 390 WP_002935902.1 hypothetical protein -
  DK877_RS01360 (DK877_01400) - 242147..242440 (+) 294 WP_002935900.1 hypothetical protein -
  DK877_RS01365 (DK877_01405) - 242815..244800 (+) 1986 WP_013730105.1 DUF1430 domain-containing protein -
  DK877_RS01370 (DK877_01410) - 244820..246802 (+) 1983 WP_009909197.1 DUF1430 domain-containing protein -
  DK877_RS01375 (DK877_01415) - 246804..247436 (+) 633 WP_009909198.1 ABC transporter ATP-binding protein -
  DK877_RS01380 (DK877_01420) - 247859..249193 (+) 1335 WP_009909199.1 sodium:alanine symporter family protein -
  DK877_RS01385 (DK877_01425) - 249275..250909 (-) 1635 WP_024409304.1 recombinase family protein -
  DK877_RS01390 (DK877_01430) - 251144..251941 (-) 798 WP_024409305.1 replication-relaxation family protein -
  DK877_RS01395 (DK877_01435) - 252029..254233 (-) 2205 Protein_244 type IV secretory system conjugative DNA transfer family protein -

Sequence


Protein


Download         Length: 237 a.a.        Molecular weight: 27200.07 Da        Isoelectric Point: 6.7422

>NTDB_id=298470 DK877_RS01230 WP_012774930.1 224437..225150(+) (treR) [Streptococcus suis strain ISU2414]
MKKYQEIYNDLKEKIRTNVYPAESSLPTEQQLQEIYGVSRDTVRKALAILTEGGLIQKVQGRGSMVLKQEILNFPVSGLT
SYQELTNVLQLSTKTDVVSLDMITVNSSLSHLTGFEPYSKVWKVVRTRSIDGKVSVVDTDYLAVDVVPELTTAIAEKSIY
EYLENKLGLDIAYAQKEITVEPTNREERELMQSKDDYLVLIKSRVYLGDTQQFQYTESKHKIDKFRFVDFARRKHSL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=298470 DK877_RS01230 WP_012774930.1 224437..225150(+) (treR) [Streptococcus suis strain ISU2414]
ATGAAAAAATACCAAGAAATTTATAATGACTTAAAAGAAAAAATACGGACAAATGTTTATCCGGCAGAAAGCTCCCTACC
GACAGAACAGCAGCTTCAGGAAATCTATGGTGTTAGTCGTGATACGGTTCGTAAGGCGTTGGCGATTTTGACTGAGGGAG
GTTTGATTCAAAAAGTGCAAGGGCGTGGTTCAATGGTCCTTAAGCAAGAAATTCTCAATTTCCCAGTTTCAGGTTTAACT
TCCTATCAGGAATTAACAAATGTTCTCCAGCTTTCTACCAAGACAGATGTTGTCAGCTTAGATATGATTACCGTTAATAG
TAGCCTTTCGCACTTGACAGGCTTTGAGCCGTATAGCAAGGTGTGGAAAGTTGTCCGTACACGTTCAATTGACGGTAAGG
TCTCCGTTGTGGATACAGATTATCTTGCTGTCGATGTCGTGCCAGAGTTGACAACTGCTATTGCTGAAAAATCCATCTAC
GAATACCTAGAAAATAAGTTAGGCCTTGATATTGCTTATGCACAAAAAGAGATTACGGTAGAGCCGACCAATCGAGAAGA
GCGTGAGCTAATGCAATCGAAGGATGATTATTTGGTCTTGATTAAATCTCGTGTCTATCTCGGTGATACCCAACAATTCC
AATATACAGAAAGCAAGCATAAAATTGATAAATTCCGCTTTGTAGATTTTGCTCGTAGAAAGCATTCTTTATAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A142UPI2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

52.137

98.734

0.515


Multiple sequence alignment