Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | DK876_RS09010 | Genome accession | NZ_CP030022 |
| Coordinates | 1846868..1849321 (-) | Length | 817 a.a. |
| NCBI ID | WP_012027858.1 | Uniprot ID | A0A2K1SY42 |
| Organism | Streptococcus suis strain ISU2714 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1842970..1886197 | 1846868..1849321 | within | 0 |
Gene organization within MGE regions
Location: 1842970..1886197
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DK876_RS08990 (DK876_09325) | dusB | 1842970..1843974 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| DK876_RS08995 (DK876_09330) | - | 1844120..1844893 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| DK876_RS09000 (DK876_09335) | pnuC | 1844886..1845707 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| DK876_RS09005 (DK876_09340) | - | 1845717..1846754 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| DK876_RS09010 (DK876_09345) | clpC | 1846868..1849321 (-) | 2454 | WP_012027858.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| DK876_RS09015 (DK876_09350) | - | 1849327..1849785 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| DK876_RS09020 (DK876_09355) | - | 1849935..1850273 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| DK876_RS09025 (DK876_09360) | - | 1850273..1850974 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| DK876_RS09030 (DK876_09365) | tsf | 1851237..1852277 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| DK876_RS09035 (DK876_09370) | rpsB | 1852433..1853209 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| DK876_RS09040 (DK876_09375) | - | 1853556..1854068 (-) | 513 | WP_012775452.1 | adenylate kinase | - |
| DK876_RS09050 (DK876_09385) | - | 1854722..1859800 (-) | 5079 | WP_012775357.1 | S8 family serine peptidase | - |
| DK876_RS09055 (DK876_09390) | nusG | 1859944..1860483 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| DK876_RS09060 (DK876_09395) | secE | 1860593..1860769 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| DK876_RS09065 (DK876_09400) | rpmG | 1860779..1860931 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| DK876_RS09070 (DK876_09405) | pbp2a | 1860965..1863178 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| DK876_RS09075 (DK876_09410) | - | 1863331..1864299 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| DK876_RS09080 (DK876_09415) | - | 1864301..1865167 (+) | 867 | WP_012027870.1 | RluA family pseudouridine synthase | - |
| DK876_RS09085 (DK876_09420) | purR | 1865194..1866006 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| DK876_RS09090 (DK876_09425) | - | 1866108..1866974 (-) | 867 | WP_012027872.1 | aminoglycoside phosphotransferase family protein | - |
| DK876_RS09095 (DK876_09430) | - | 1866974..1867915 (-) | 942 | WP_044475302.1 | 3'-5' exoribonuclease YhaM family protein | - |
| DK876_RS09100 (DK876_09435) | - | 1867905..1869143 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| DK876_RS09105 (DK876_09440) | - | 1869144..1869776 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| DK876_RS09110 (DK876_09445) | rpe | 1869769..1870428 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| DK876_RS09115 (DK876_09450) | rsgA | 1870443..1871318 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| DK876_RS09125 (DK876_09460) | - | 1872215..1873792 (-) | 1578 | WP_012027878.1 | ABC transporter ATP-binding protein | - |
| DK876_RS09130 (DK876_09465) | - | 1873789..1875030 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| DK876_RS09135 (DK876_09470) | - | 1875399..1876262 (-) | 864 | WP_012027880.1 | helix-turn-helix domain-containing protein | - |
| DK876_RS09140 (DK876_09480) | - | 1876752..1879196 (-) | 2445 | WP_012027881.1 | LTA synthase family protein | - |
| DK876_RS09145 (DK876_09485) | - | 1879209..1880939 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| DK876_RS09150 (DK876_09490) | rsmA | 1881304..1882176 (-) | 873 | WP_012775362.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| DK876_RS09155 (DK876_09495) | - | 1882196..1882726 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| DK876_RS09160 (DK876_09500) | - | 1882740..1882997 (-) | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
| DK876_RS09165 (DK876_09505) | - | 1882999..1883259 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| DK876_RS09170 (DK876_09510) | - | 1883335..1883790 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| DK876_RS09175 (DK876_09515) | - | 1883797..1884126 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| DK876_RS09180 (DK876_09520) | - | 1884116..1884403 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| DK876_RS09185 (DK876_09525) | - | 1884501..1884869 (-) | 369 | WP_012775453.1 | hypothetical protein | - |
| DK876_RS09190 (DK876_09530) | rnmV | 1884862..1885431 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| DK876_RS09195 (DK876_09535) | - | 1885415..1886197 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90132.53 Da Isoelectric Point: 6.3138
>NTDB_id=298448 DK876_RS09010 WP_012027858.1 1846868..1849321(-) (clpC) [Streptococcus suis strain ISU2714]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=298448 DK876_RS09010 WP_012027858.1 1846868..1849321(-) (clpC) [Streptococcus suis strain ISU2714]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae Rx1 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae D39 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus mutans UA159 |
66.173 |
99.143 |
0.656 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.828 |
99.878 |
0.647 |
| clpC | Streptococcus thermophilus LMD-9 |
64.706 |
99.878 |
0.646 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.086 |
100 |
0.492 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.403 |
99.51 |
0.442 |