Detailed information NTG0298423

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DK876_RS02405
• Genome accession: NZ_CP030022
• Coordinates: 479915..482143 (-)
• Length: 742 a.a.
• NCBI ID: WP_044475287.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2714
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 474915..487143

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK876_RS02385 (DK876_02475)	-	475283..475726 (+)	444	WP_012774999.1	GNAT family N-acetyltransferase	-
DK876_RS02390 (DK876_02480)	ileS	475737..478526 (+)	2790	WP_012775000.1	isoleucine--tRNA ligase	-
DK876_RS02395 (DK876_02485)	-	478905..479213 (-)	309	WP_002938710.1	DUF1827 family protein	-
DK876_RS02400 (DK876_02490)	-	479268..479729 (-)	462	WP_002938708.1	NUDIX hydrolase	-
DK876_RS02405 (DK876_02495)	clpE	479915..482143 (-)	2229	WP_044475287.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DK876_RS02410 (DK876_02500)	-	482367..482597 (+)	231	WP_002938704.1	DUF1797 family protein	-
DK876_RS02415 (DK876_02505)	-	482723..483412 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
DK876_RS02420 (DK876_02510)	-	483405..484139 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
DK876_RS02425 (DK876_02515)	-	484269..485117 (+)	849	WP_011922050.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
DK876_RS02430 (DK876_02525)	-	486566..486859 (+)	294	WP_002938694.1	hypothetical protein	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82638.01 Da
• Isoelectric Point: 5.4248

>NTDB_id=298423 DK876_RS02405 WP_044475287.1 479915..482143(-) (clpE) [Streptococcus suis strain ISU2714]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPHNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEITRRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDSENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVSLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYNPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=298423 DK876_RS02405 WP_044475287.1 479915..482143(-) (clpE) [Streptococcus suis strain ISU2714]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTCATAATGCTATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTACCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAATCCTGTTCTTATCGGTGAGCCTGGGGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAAAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATCCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAATCGCTACATTCAAGACCGTTTCCTACCAGACAAGGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATTCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCAGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAAGAAGATATTCCACTCATTACTGAAAAAGAAATTGAAGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAGCCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGTTCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTTCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGATGATGGGCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACAATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (291-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	81.83	100	0.832
clpE	Streptococcus pneumoniae D39	81.83	100	0.832
clpE	Streptococcus pneumoniae R6	81.83	100	0.832
clpE	Streptococcus pneumoniae TIGR4	81.83	100	0.832
clpE	Streptococcus mutans UA159	81.976	100	0.827
clpC	Lactococcus lactis subsp. cremoris KW2	77.379	97.709	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	52	87.601	0.456
clpC	Streptococcus thermophilus LMD-9	47.771	84.636	0.404
clpC	Streptococcus mutans UA159	48.077	84.097	0.404
clpC	Streptococcus thermophilus LMG 18311	47.452	84.636	0.402
clpC	Streptococcus pneumoniae D39	47.36	84.232	0.399
clpC	Streptococcus pneumoniae TIGR4	47.36	84.232	0.399
clpC	Streptococcus pneumoniae Rx1	47.36	84.232	0.399
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.178	84.636	0.391