Detailed information NTG0298379

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DK875_RS07975
• Genome accession: NZ_CP030020
• Coordinates: 1613756..1614805 (-)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain ISU2514
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1608756..1619805

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK875_RS07955 (DK875_08280)	nadE	1609584..1610408 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
DK875_RS07960 (DK875_08285)	-	1611282..1611809 (-)	528	WP_004194600.1	VanZ family protein	-
DK875_RS07965 (DK875_08290)	rlmN	1611806..1612918 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DK875_RS07970 (DK875_08295)	-	1612927..1613568 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
DK875_RS07975 (DK875_08300)	sepM	1613756..1614805 (-)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
DK875_RS07980 (DK875_08305)	coaD	1614792..1615280 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
DK875_RS07985 (DK875_08310)	rsmD	1615270..1615809 (-)	540	WP_024394248.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DK875_RS07990 (DK875_08315)	-	1616108..1616830 (-)	723	WP_013730502.1	hypothetical protein	-
DK875_RS07995 (DK875_08320)	-	1616887..1617273 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
DK875_RS08000 (DK875_08325)	-	1617273..1617491 (-)	219	WP_004194736.1	YqgQ family protein	-
DK875_RS08005 (DK875_08330)	-	1617791..1618393 (-)	603	WP_004194738.1	response regulator transcription factor	-
DK875_RS08010 (DK875_08335)	-	1618390..1619484 (-)	1095	WP_004194740.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=298379 DK875_RS07975 WP_004194592.1 1613756..1614805(-) (sepM) [Streptococcus suis strain ISU2514]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=298379 DK875_RS07975 WP_004194592.1 1613756..1614805(-) (sepM) [Streptococcus suis strain ISU2514]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605