Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DK875_RS01455 Genome accession   NZ_CP030020
Coordinates   267595..270048 (+) Length   817 a.a.
NCBI ID   WP_002937803.1    Uniprot ID   A0A075SJA7
Organism   Streptococcus suis strain ISU2514     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 262595..275048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK875_RS01430 (DK875_01465) rpsB 263656..264432 (+) 777 WP_002937818.1 30S ribosomal protein S2 -
  DK875_RS01435 (DK875_01470) tsf 264628..265668 (+) 1041 WP_002937816.1 translation elongation factor Ts -
  DK875_RS01440 (DK875_01475) - 265824..266525 (-) 702 WP_002937813.1 hypothetical protein -
  DK875_RS01445 (DK875_01480) - 266525..266863 (-) 339 WP_002937812.1 thioredoxin domain-containing protein -
  DK875_RS01450 (DK875_01485) - 267133..267591 (+) 459 WP_002937810.1 CtsR family transcriptional regulator -
  DK875_RS01455 (DK875_01490) clpC 267595..270048 (+) 2454 WP_002937803.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DK875_RS01460 (DK875_01495) - 270167..270658 (+) 492 WP_002937801.1 adenylyltransferase/cytidyltransferase family protein -
  DK875_RS01465 (DK875_01500) - 270856..271239 (+) 384 WP_002937798.1 hypothetical protein -
  DK875_RS01470 (DK875_01505) - 271259..271492 (+) 234 WP_002937793.1 hypothetical protein -
  DK875_RS01475 (DK875_01510) - 271489..271731 (+) 243 WP_002937789.1 hypothetical protein -
  DK875_RS01480 (DK875_01515) dusB 271845..272849 (-) 1005 WP_002937787.1 tRNA dihydrouridine synthase DusB -
  DK875_RS01485 (DK875_01520) hslO 272842..273708 (-) 867 WP_053866407.1 Hsp33 family molecular chaperone HslO -

Sequence

Protein


Download         Length: 817 a.a.        Molecular weight: 90368.85 Da        Isoelectric Point: 6.0792

>NTDB_id=298352 DK875_RS01455 WP_002937803.1 267595..270048(+) (clpC) [Streptococcus suis strain ISU2514]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFIVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNVEARAGFTKEDLK
AIRSVMKGGKAKPANMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTESDMQDVVKVMVKPLFAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLATGST
LKVGVKGEELKFDVVKG

Nucleotide


Download         Length: 2454 bp        

>NTDB_id=298352 DK875_RS01455 WP_002937803.1 267595..270048(+) (clpC) [Streptococcus suis strain ISU2514]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGCTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTATTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACGTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTGCCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ATGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCAACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTTG
AGGACAGTATTGCCATTTTGACAGGGCTTAAAGGTACTTTTGAGAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTACCGGATTCAGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTCTTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTGTCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAGGCCTACCGTCCTGAATTTATCAACCGTATTGATGAAAAAGTTGTCTTC
CATAGTTTGACCGAATCCGATATGCAGGATGTTGTCAAGGTCATGGTCAAACCGTTGTTTGCGGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTACGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTACAAACCAAATTGGAAGATCCGTTGGCAGAAATGTTGCTCCGTGGTGACTTGGCTACTGGTTCGACC
CTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(372-457)

ATPase family associated with various cellular activities (AAA) (AAA)

(233-365)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(723-803)

AAA domain (Cdc48 subfamily) (AAA_2)

(545-716)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(102-129)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-56)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SJA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

71.779

99.755

0.716
  clpC Streptococcus pneumoniae D39

71.779

99.755

0.716
  clpC Streptococcus pneumoniae TIGR4

71.779

99.755

0.716
  clpC Streptococcus mutans UA159

67.076

99.633

0.668
  clpC Streptococcus thermophilus LMD-9

64.081

100

0.657
  clpC Streptococcus thermophilus LMG 18311

64.501

100

0.656
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

49.281

100

0.503
  clpC Bacillus subtilis subsp. subtilis str. 168

43.114

100

0.441

Multiple sequence alignment