Detailed information NTG0298333

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DK235_RS07765
• Genome accession: NZ_CP030017
• Coordinates: 1573440..1574489 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain ISU1606
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1568440..1579489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK235_RS07745 (DK235_08030)	nadE	1568846..1569670 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
DK235_RS07750 (DK235_08035)	-	1570966..1571493 (-)	528	WP_012027591.1	VanZ family protein	-
DK235_RS07755 (DK235_08040)	rlmN	1571490..1572602 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DK235_RS07760 (DK235_08045)	-	1572611..1573252 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
DK235_RS07765 (DK235_08050)	sepM	1573440..1574489 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
DK235_RS07770 (DK235_08055)	coaD	1574476..1574964 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
DK235_RS07775 (DK235_08060)	rsmD	1574954..1575493 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DK235_RS07780 (DK235_08065)	-	1575801..1576523 (-)	723	WP_012027598.1	lipoprotein	-
DK235_RS07785 (DK235_08070)	-	1576580..1576966 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
DK235_RS07790 (DK235_08075)	-	1576966..1577184 (-)	219	WP_004194736.1	YqgQ family protein	-
DK235_RS07795 (DK235_08080)	-	1577492..1578094 (-)	603	WP_044667065.1	response regulator transcription factor	-
DK235_RS07800 (DK235_08085)	-	1578091..1579185 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=298333 DK235_RS07765 WP_012775295.1 1573440..1574489(-) (sepM) [Streptococcus suis strain ISU1606]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=298333 DK235_RS07765 WP_012775295.1 1573440..1574489(-) (sepM) [Streptococcus suis strain ISU1606]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605