Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   ESP48_RS10065 Genome accession   NZ_CP035306
Coordinates   652025..652828 (+) Length   267 a.a.
NCBI ID   WP_223899638.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain IDCC2201     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 647025..657828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ESP48_RS03445 (ESP48_03445) - 647609..647863 (-) 255 WP_014608660.1 Blp family class II bacteriocin -
  ESP48_RS10485 (ESP48_03450) - 648114..648515 (-) 402 WP_024703992.1 hypothetical protein -
  ESP48_RS03460 (ESP48_03460) - 649520..649750 (-) 231 WP_014608662.1 bacteriocin class II family protein -
  ESP48_RS03465 (ESP48_03465) - 650106..650306 (-) 201 WP_011681569.1 hypothetical protein -
  ESP48_RS03470 (ESP48_03470) - 650325..650501 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  ESP48_RS03475 (ESP48_03475) - 650757..651494 (+) 738 WP_064356014.1 LytR/AlgR family response regulator transcription factor -
  ESP48_RS10065 comD/blpH 652025..652828 (+) 804 WP_223899638.1 ATP-binding protein Regulator
  ESP48_RS03485 (ESP48_03485) - 652846..653007 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ESP48_RS03490 (ESP48_03490) comB 653022..654389 (-) 1368 WP_064356015.1 bacteriocin secretion accessory protein Regulator
  ESP48_RS03495 (ESP48_03495) comA/nlmT 654405..656558 (-) 2154 WP_041827378.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30641.92 Da        Isoelectric Point: 4.7379

>NTDB_id=298201 ESP48_RS10065 WP_223899638.1 652025..652828(+) (comD/blpH) [Streptococcus thermophilus strain IDCC2201]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=298201 ESP48_RS10065 WP_223899638.1 652025..652828(+) (comD/blpH) [Streptococcus thermophilus strain IDCC2201]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATTGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAAAAAACAGAAA
CCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment