Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EQH15_RS05460 Genome accession   NZ_CP035265
Coordinates   1078397..1078861 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain TVO_1901920     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1073397..1083861
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH15_RS05440 (EQH15_05730) - 1074348..1075316 (-) 969 WP_000105371.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  EQH15_RS05445 (EQH15_05735) pdrM 1075470..1076831 (-) 1362 WP_000278533.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  EQH15_RS05450 (EQH15_05740) - 1076842..1077102 (-) 261 WP_001105925.1 hypothetical protein -
  EQH15_RS05455 (EQH15_05745) - 1077116..1078384 (-) 1269 WP_000924486.1 dihydroorotase -
  EQH15_RS05460 (EQH15_05750) mutX 1078397..1078861 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  EQH15_RS05465 (EQH15_05755) - 1078871..1079524 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  EQH15_RS05470 (EQH15_05765) - 1079860..1080264 (-) 405 WP_000005501.1 hypothetical protein -
  EQH15_RS05475 (EQH15_05770) - 1080322..1081035 (-) 714 WP_000499432.1 YjjG family noncanonical pyrimidine nucleotidase -
  EQH15_RS05480 (EQH15_05775) dhaM 1081493..1081873 (-) 381 Protein_1096 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EQH15_RS10930 - 1081873..1081947 (-) 75 Protein_1097 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=298030 EQH15_RS05460 WP_001135768.1 1078397..1078861(-) (mutX) [Streptococcus pneumoniae strain TVO_1901920]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=298030 EQH15_RS05460 WP_001135768.1 1078397..1078861(-) (mutX) [Streptococcus pneumoniae strain TVO_1901920]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987