Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EQH17_RS05400 Genome accession   NZ_CP035263
Coordinates   1080546..1081010 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain TVO_1901922     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1075546..1086010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH17_RS11045 - 1077466..1077540 (+) 75 Protein_1079 dihydroxyacetone kinase subunit L -
  EQH17_RS05380 (EQH17_05685) dhaM 1077540..1077914 (+) 375 WP_000443795.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EQH17_RS05385 (EQH17_05690) - 1078374..1079087 (+) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  EQH17_RS05390 (EQH17_05695) - 1079145..1079747 (+) 603 WP_001810555.1 hypothetical protein -
  EQH17_RS05395 (EQH17_05700) - 1079883..1080536 (+) 654 WP_000401326.1 uracil-DNA glycosylase -
  EQH17_RS05400 (EQH17_05705) mutX 1080546..1081010 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  EQH17_RS05405 (EQH17_05710) - 1081023..1082291 (+) 1269 WP_000924498.1 dihydroorotase -
  EQH17_RS05410 (EQH17_05715) - 1082305..1082565 (+) 261 WP_001105925.1 hypothetical protein -
  EQH17_RS05415 (EQH17_05720) pdrM 1082576..1083946 (+) 1371 WP_061632321.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  EQH17_RS05420 (EQH17_05725) - 1084100..1085068 (+) 969 WP_000105361.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=297793 EQH17_RS05400 WP_001135768.1 1080546..1081010(+) (mutX) [Streptococcus pneumoniae strain TVO_1901922]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=297793 EQH17_RS05400 WP_001135768.1 1080546..1081010(+) (mutX) [Streptococcus pneumoniae strain TVO_1901922]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCTAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987