Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SPJ_RS05435 Genome accession   NC_012466
Coordinates   1052556..1053020 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae JJA     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1047556..1058020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPJ_RS05415 (SPJ_1083) - 1048507..1049475 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  SPJ_RS05420 (SPJ_1084) pdrM 1049629..1050990 (-) 1362 WP_000278527.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  SPJ_RS05425 - 1051001..1051261 (-) 261 WP_001105925.1 hypothetical protein -
  SPJ_RS05430 (SPJ_1085) - 1051275..1052543 (-) 1269 WP_000924487.1 dihydroorotase -
  SPJ_RS05435 (SPJ_1086) mutX 1052556..1053020 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  SPJ_RS05440 (SPJ_1087) - 1053030..1053683 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  SPJ_RS05445 (SPJ_1089) - 1054019..1054423 (-) 405 WP_000005501.1 hypothetical protein -
  SPJ_RS05450 (SPJ_1090) - 1054481..1055194 (-) 714 WP_000499432.1 YjjG family noncanonical pyrimidine nucleotidase -
  SPJ_RS11890 (SPJ_1091) dhaM 1055652..1056032 (-) 381 Protein_1044 dihydroxyacetone kinase phosphoryl donor subunit DhaM -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=29775 SPJ_RS05435 WP_001135768.1 1052556..1053020(-) (mutX) [Streptococcus pneumoniae JJA]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=29775 SPJ_RS05435 WP_001135768.1 1052556..1053020(-) (mutX) [Streptococcus pneumoniae JJA]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment